Serial interval distribution of SARS-CoV-2 infection in Brazil

Prete, Carlos A.; Buss, Lewis; Dighe, Amy; Pôrto, Victor Bertollo Gomes; Cândido, Darlan da Silva; Ghilardi, Fábio; Pybus, Oliver G.; Oliveira, Wanderson Kleber de; Croda, Júlio; Sabino, Éster Cerdeira; Faria, Nuno Rodrigues; Donnelly, Christl A.; Nascimento, Vítor H.

doi:10.1093/jtm/taaa115

Cited by 40 publications

(33 citation statements)

References 7 publications

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“…Of the shortlisted studies, most relate to Asian countries, particularly China. Apart from the study by Lavezzo et al 1 which deals solely with the COVID-19 outbreak in Italy, the study by Prete et al 2 from Brazil and the study by Böhmer et al 3 from Germany, the number of datapoints from the non-Asian countries was very small.…”

Section: Resultsmentioning

confidence: 95%

“…A total of 38 estimates are provided for the mean of the serial interval. These range from 3.03 2 to 7.6 9 days. A total of 15 estimates are provided for the median of the serial interval.…”

Section: Resultsmentioning

confidence: 99%

“…The published studies consisted of 28 research articles, 1 3–29 4 letters, 2 30–32 2 reports, 33 34 a brief communication, 35 3 accepted manuscripts 36–38 and 2 pre-proofs. 39 40 …”

Section: Resultsmentioning

confidence: 99%

“…Instead, typically, the onset of symptoms is observed. The estimates for the mean of the serial interval ranged from 3.03 2 to 7.6 9 days. There are a number of reasons why the estimates are wide ranging.…”

Section: Discussionmentioning

confidence: 99%

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Rapid review of available evidence on the serial interval and generation time of COVID-19

et al. 2020

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The serial interval is the time between symptom onsets in an infector–infectee pair. The generation time, also known as the generation interval, is the time between infection events in an infector–infectee pair. The serial interval and the generation time are key parameters for assessing the dynamics of a disease. A number of scientific papers reported information pertaining to the serial interval and/or generation time for COVID-19. Objective Conduct a review of available evidence to advise on appropriate parameter values for serial interval and generation time in national COVID-19 transmission models for Ireland and on methodological issues relating to those parameters. Methods We conducted a rapid review of the literature covering the period 1 January 2020 and 21 August 2020, following predefined eligibility criteria. Forty scientific papers met our inclusion criteria and were included in the review. Results The mean of the serial interval ranged from 3.03 to 7.6 days, based on 38 estimates, and the median from 1.0 to 6.0 days (based on 15 estimates). Only three estimates were provided for the mean of the generation time. These ranged from 3.95 to 5.20 days. One estimate of 5.0 days was provided for the median of the generation time. Discussion Estimates of the serial interval and the generation time are very dependent on the specific factors that apply at the time that the data are collected, including the level of social contact. Consequently, the estimates may not be entirely relevant to other environments. Therefore, local estimates should be obtained as soon as possible. Careful consideration should be given to the methodology that is used. Real-time estimations of the serial interval/generation time, allowing for variations over time, may provide more accurate estimates of reproduction numbers than using conventionally fixed serial interval/generation time distributions.

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Section: Resultsmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

“…The published studies consisted of 28 research articles, 1 3–29 4 letters, 2 30–32 2 reports, 33 34 a brief communication, 35 3 accepted manuscripts 36–38 and 2 pre-proofs. 39 40 …”

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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