Serological investigations in an area of endemic filariasis due to Wuchereria bancrofti and Acanthocheilonema perstans in Gambia, West Africa

Minning, W.; McFadzean, James A.

doi:10.1016/0035-9203(56)90031-1

Cited by 6 publications

(1 citation statement)

References 9 publications

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“…A striking feature of the antibody response of cats to B. pahangi infection was that relatively high antibody titres were recorded in the two cats which did not develop microfilariae. In human tropical pulmonary eosinophilia no microfilariae are found in the blood but strong serological reactions are evinced (Minning and McFadzean, 1956;Danaraj and Schacher, 1959;Lie Kian Joe, 1962;Jayewardene and Wijayaratnam, 1968;Wong and Guest,,1969).…”

Section: Discussionmentioning

confidence: 99%

Studies with Brugia pahangi 4. Antibodies against adult and microfilarial stages

Ponnudurai¹,

Denham²,

Nelson³

et al. 1974

J. Helminthol.

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Using the indirect fluorescent antibody technique, the antibody response of cats to Brugia pahangi infections was studied using whole microfilariae and sectioned adult worms of B. pahangi as antigens. Microfilarial antigen was ineffective in detecting antibody response in cats during the microfilaraemic phase of the infection, although it was possible to detect circulating antibody in cats which became microfilaria negative after repeated and prolonged reinfection and in one cat which after infection failed to show microfilariae in its blood

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Section: Discussionmentioning

confidence: 99%

Studies with Brugia pahangi 4. Antibodies against adult and microfilarial stages

Ponnudurai¹,

Denham²,

Nelson³

et al. 1974

J. Helminthol.

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Advances in methodology for immunodiagnosis of parasitic diseases

Fife

1971

Experimental Parasitology

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Mansonella perstans filariasis in Africa

2011

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Mansonella perstans is a vector-borne human filarial nematode, transmitted by tiny blood-sucking flies (biting midges). It is widespread in many parts of Sub-Saharan Africa and also occurs in parts of Central and South America. Despite the commonness of this parasite very few studies have been carried out on its epidemiology and on the morbidity resulting from it, and only few thorough drug trials have been conducted to look for effective and suitable drugs and drug regimens for treatment and control. Here, we review currently available knowledge on M. perstans infections in Africa, including documented aspects of biology, vectors, transmission, diagnosis, epidemiology, morbidity and treatment. It is concluded that there is an urgent need for more research on this widespread but greatly neglected infection in order to properly assess its public health significance and as a background for identifying and recommending optimal means and strategies for treatment and control.

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Serological investigations in an area of endemic filariasis due to Wuchereria bancrofti and Acanthocheilonema perstans in Gambia, West Africa

Cited by 6 publications

References 9 publications

Studies with Brugia pahangi 4. Antibodies against adult and microfilarial stages

Studies with Brugia pahangi 4. Antibodies against adult and microfilarial stages

Advances in methodology for immunodiagnosis of parasitic diseases

Mansonella perstans filariasis in Africa

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