Simplified method for polarization-sensitive optical coherence tomography

Roth, Jonathan E.; Kozak, Jennifer A.; Yazdanfar, Siavash; Rollins, Andrew M.; Izatt, Joseph A.

doi:10.1364/ol.26.001069

Cited by 76 publications

(57 citation statements)

References 9 publications

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“…Comparison of the Stokes parameters of the incident state to that reflected from the sample can yield a depth-resolved map of optical properties such as birefringence [8]. PS-OCT has been incorporated in fiber-based systems using standard single-mode fiber [10,11] and using polarization-maintaining fiber [12,13]. Another extension, optical Doppler tomography (ODT), is capable of depth-resolved imaging of flow [14][15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Real-time multi-functional optical coherence tomography

Park¹,

Pierce²,

Cense³

et al. 2003

Opt. Express

160

122

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Abstract:We demonstrate real-time acquisition, processing, and display of tissue structure, birefringence, and blood flow in a multi-functional optical coherence tomography (MF-OCT) system. This is accomplished by efficient data processing of the phase-resolved inteference patterns without dedicated hardware or extensive modification to the high-speed fiber-based OCT system. The system acquires images of 2048 depth scans per second, covering an area of 5 mm in width × 1.2 mm in depth with real-time display updating images in a rolling manner 32 times each second. We present a video of the system display as images from the proximal nail fold of a human volunteer are taken.

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Section: Introductionmentioning

confidence: 99%

Real-time multi-functional optical coherence tomography

Park¹,

Pierce²,

Cense³

et al. 2003

Opt. Express

160

122

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“…polarization sensitive imaging were designed [80][81][82][83]. In addition to the embodiments that measure the absolute polarization state of the light, there is a less complex approach to determine relative birefringence in a sample [83,84].…”

Section: Polarization Sensitive Octmentioning

confidence: 99%

Optical coherence tomography—current technology and applications in clinical and biomedical research

et al. 2011

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Optical coherence tomography (OCT) is a non-invasive imaging technique providing real-time twoand three-dimensional images of scattering samples with micrometer resolution. Mapping the local reflectivity, OCT visualizes the morphology of the sample. In addition, functional properties such as birefringence, motion or the distribution of certain substances can be detected with high spatial resolution. The main field of application is bio-medical imaging and diagnostics. In ophthalmology, OCT is accepted as a clinical standard for diagnosing and monitoring treatment of a number of retinal diseases, and OCT is becoming an important instrument for clinical cardiology. New applications are emerging in various medical fields, e. g. early-stage cancer detection, surgical guidance, and early diagnosis of musculoskeletal diseases. OCT has also proven its value as a tool for developmental biology. The number of companies involved in manufacturing OCT systems has increased substantially during the last years-especially due to its success in opthalmology-and this technology can be expected to continue to spread into various fields of application.

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“…Initially, OCT was applied in ophthalmology [14,15] Sensitive OCT (PS-OCT) [22,23], able to extract the birefringence properties of biological tissues and wavelength dependent OCT modalities, like refractometric OCT [24] or spectroscopic OCT [25,26]. What is more, OCT can be interfaced to a wide range of commercially available and customized instruments such as endoscopes, catheters, or laparoscopes, which enable the imaging of internal organ systems [27,28].…”

Section: 2mentioning

confidence: 99%