Simultaneous Bilateral Retinal Arterial Occlusions Treated by Exchange Transfusions

Superior macular sparing in central retinal artery occlusion due to sickle cell anaemia

“…It has been successfully performed in a 25-year-old patient with bilateral central retinal artery occlusions 8 h postocclusion. 3 In this case, exchange transfusion was not felt to be beneficial because of the late stage of presentation. Reperfusion may have been established, but retinal function in the infracted area would not have recovered.…”

Central retinal artery occlusion in homozygous sickle cell (SS) disease

“…There are several previous reports of central retinal artery occlusion arising in homozygous sickle cell disease (Acacio & Goldberg 1973;Weissman, Nadel & Dunn 1979;Napp 1972;Jompal et al 1981). In four cases sudden painless loss of vision was described, and in the fifth, visual loss was slowly progressive over 3 weeks.…”

Concurrent Bilateral Central Retinal Artery Occlusion Secondary to Sickle Cell Crisis

“… 16 While delivered through exchange transfusion, the normal RBCs being pliable squeeze through the partially blocked arterioles and deliver the oxygen to the distal tissues, thereby reverting the symptoms. 17 …”