Solubility of Amino Acids:  Influence of the pH value and the Addition of Alcoholic Cosolvents on Aqueous Solubility

Fuchs, D.; Fischer, Jan; Tumakaka, Feelly; Sadowski, Gabriele

doi:10.1021/ie0602097

Cited by 189 publications

(181 citation statements)

References 32 publications

Supporting

Mentioning

176

Contrasting

Unclassified

Order By: Relevance

“…These parameters are applied to predict single-sugar solubility in pure solvents (water, ethanol, or methanol) and in solvent mixtures (water/ethanol, water/methanol) as well as osmotic coefficients in aqueous solutions containing two or more sugars. This study uses the Perturbed-Chain Statistical Association Fluid Theory (PC-SAFT) framework because it has already proven flexibility and performance in modeling complex systems containing biomolecules (amino acids, [14][15][16] osmolytes, 17 urea 18 ) as well as electrolytes [19][20][21][22] in aqueous solutions. The pure-component parameters of the sugars were determined by fitting to experimental solution densities and osmotic coefficients of binary sugar/water mixtures only.…”

mentioning

confidence: 99%

Modeling thermodynamic properties of aqueous single‐solute and multi‐solute sugar solutions with PC‐SAFT

et al. 2013

Self Cite

View full text Add to dashboard Cite

The Perturbed-Chain Statistical Association Fluid Theory is applied to simultaneously describe various thermodynamic properties (solution density, osmotic coefficient, solubility) of aqueous solutions containing a monosaccharide or a disaccharide. The 13 sugars considered within this work are: glucose, fructose, fucose, xylose, maltose, mannitol, mannose, sorbitol, xylitol, galactose, lactose, trehalose, and sucrose. Four adjustable parameters (three pure-sugar parameters and a k ij between sugar and water that was allowed to depend linearly on temperature) were obtained from solution densities and osmotic coefficients of binary sugar/water solutions at 298.15 K available in literature. Using these parameters, the sugar solubility in water and in ethanol could be predicted satisfactorily. Further, osmotic coefficients and solubility in aqueous solutions containing two solutes (sugar/sugar, sugar/salt) were predicted (no additional k ij parameters between the two solutes) reasonably. The model was also applied to predict the solubility of a sugar in a solvent mixture (e.g., water/ethanol) without additional fitting parameters. V C 2013 American Institute of Chemical Engineers AIChE J, 59: [4794][4795][4796][4797][4798][4799][4800][4801][4802][4803][4804][4805] 2013

show abstract

mentioning

confidence: 99%

Modeling thermodynamic properties of aqueous single‐solute and multi‐solute sugar solutions with PC‐SAFT

et al. 2013

Self Cite

View full text Add to dashboard Cite

show abstract

“…Meanwhile, chemical analyses suggest that the protein-like fluorophores consist primarily of proteinaceous materials (e.g., proteins and peptides; Yamashita and Tanoue, 2003;Maie et al, 2007), and this DOC fraction is generally hydrophilic and low molecular weight (LMW) compounds (e.g., Sommerville and Preston, 2001). Results of Chen et al (1989) and Fuchs et al (2006) showed that solubility of the proteinaceous materials in LMW is generally affected by neither pH within the normal range of 6-9 nor colloid coagulation. Therefore, increasing ionic strength (or salinization) can enhance the solubility of the proteinaceous materials via sodium dispersion (Green et al, 2008(Green et al, , 2009a or through nonspecific electrostatic interactions at low salinities (called a "salting-in" effect) (Tanford, 1961;Chen et al, 1989).…”

Section: S Duan and S S Kaushal: Salinization Alters Fluxes Of Biomentioning

confidence: 97%

Salinization alters fluxes of bioreactive elements from stream ecosystems across land use

Duan

Kaushal

2015

Biogeosciences

View full text Add to dashboard Cite

Abstract. There has been increased salinization of fresh water over decades due to the use of road salt deicers, wastewater discharges, saltwater intrusion, human-accelerated weathering, and groundwater irrigation. Salinization can mobilize bioreactive elements (carbon, nitrogen, phosphorus, sulfur) chemically via ion exchange and/or biologically via influencing of microbial activity. However, the effects of salinization on coupled biogeochemical cycles are still not well understood. We investigated potential impacts of increased salinization on fluxes of bioreactive elements from stream ecosystems (sediments and riparian soils) to overlying stream water and evaluated the implications of percent urban land use on salinization effects. Two-day incubations of sediments and soils with stream and deionized water across three salt levels were conducted at eight routine monitoring stations across a land-use gradient at the Baltimore Ecosystem Study Long-Term Ecological Research (LTER) site in the Chesapeake Bay watershed. Results indicated (1) salinization typically increased sediment releases of labile dissolved organic carbon (DOC), dissolved inorganic carbon (DIC), total dissolved Kjeldahl nitrogen (TKN) (ammonium + ammonia + dissolved organic nitrogen), and sediment transformations of nitrate; (2) salinization generally decreased DOC aromaticity and fluxes of soluble reactive phosphorus from both sediments and soils; (3) the effects of increased salinization on sediment releases of DOC and TKN and DOC quality increased with percentage watershed urbanization. Biogeochemical responses to salinization varied between sediments and riparian soils in releases of DOC and DIC, and nitrate transformations. The differential responses of riparian soils and sediments to increased salinization were likely due to differences in organic matter sources and composition. Our results suggest that short-term increases in salinization can cause releases of significant amounts of labile organic carbon and nitrogen from stream substrates and organic transformations of nitrogen and phosphorus in urban watersheds. Given that salinization of fresh water will increase in the future due to human activities, significant impacts on carbon and nutrient mobilization and water quality should be anticipated.

show abstract

“…The high peptide-binding ability of DBC can be attributed to both covalent and noncovalent interactions with Col-p. There is also an increase in the uncharged amino groups (NH 2 ) of amino acids with increased pH, 30 such as lysine and arginine, which enables Col-p to be immobilized on DBC through aldehyde groups. It is well known that aldehydic groups can covalently cross-link with collagen by amino functional groups of the protein.…”

Section: Effects Of Do Ph and Zeta Potential On Peptide-bindingmentioning

confidence: 99%

Immobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration

Wen¹,

Zheng²,

Wu³

et al. 2015

IJN

View full text Add to dashboard Cite

Bacterial cellulose (BC) is an alternative nanostructured biomaterial to be utilized for a wide range of biomedical applications. Because of its low bioactivity, which restricted its practical application, collagen and collagen hydrolysate were usually composited into BC. It is necessary to develop a new method to generate covalent bonds between collagen and cellulose to improve the immobilization of collagen on BC. This study describes a facile dialdehyde BC/collagen peptide nanocomposite. BC was oxidized into dialdehyde bacterial cellulose (DBC) by regioselective oxidation, and then composited with collagen peptide (Col-p) via covalent bonds to form Schiff’s base type compounds, which was demonstrated by the results of microstructures, contact angle, Col-p content, and peptide-binding ratio. The peptide-binding ratio was further affected by the degree of oxidation, pH value, and zeta potential. In vitro desorption measurement of Col-p suggested a controlled release mechanism of the nanocomposite. Cell tests indicated that the prepared DBC/Col-p composite was bioactive and suitable for cell adhesion and attachment. This work demonstrates that the DBC/Col-p composite is a promising material for tissue engineering and regeneration.

show abstract

Solubility of Amino Acids: Influence of the pH value and the Addition of Alcoholic Cosolvents on Aqueous Solubility

Cited by 189 publications

References 32 publications

Modeling thermodynamic properties of aqueous single‐solute and multi‐solute sugar solutions with PC‐SAFT

Modeling thermodynamic properties of aqueous single‐solute and multi‐solute sugar solutions with PC‐SAFT

Salinization alters fluxes of bioreactive elements from stream ecosystems across land use

Immobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration

Contact Info

Product

Resources

About