Telemedicine provides an attractive
vision for tele-monitoring
human health conditions and, thus, offers the opportunity for timely
preventing chronic disease. A key limitation of promoting telemedicine
in clinic application is the lack of a noninvasive med-tech and effective
monitoring platform, which should be wearable and capable of high-performance
tele-monitoring of health risk. Here we proposed a volatolomics-based
telemedicine for continuously and noninvasively assessing human health
status through continuously tracking the variation of volatile markers
derived from human breath or skin. Particularly, a nanosensor-based
flexible electronic was specifically designed to serve as a powerful
platform for implementing the proposed cost-effective healthcare.
An all-flexible and highly packed makeup (all functional units were
integrated in a 2*2*0.19 cm3 plate) enables an electronic,
compact configuration and the capability of resisting negative impact
derived from customers’ daily movement. Notably, the nanosensor-based
electronic demonstrates high specificity,
quick response rate (t
90% = 4.5 s), and
desirable low detection limit (down to 0.117 ppm) in continuous tele-monitoring
chronic-disease-related volatile marker (e.g., acetone). Assisted
by the power saved light fidelity (Li-Fi) communicating technology,
a clinic proof on the specifically designed electronic for noninvasively
and uninterrupted assessing potential health risk (e.g., diabetics)
is successfully implemented, with the accuracy of around 81%. A further
increase in the accuracy of prewarning is predicted by excluding the
impact of individual differences such as the gender, age, and smoking
status of the customer. These promising pilot results indicate a bright
future for the tailor-made nanosensing-device-supported volatolomics-based
telemedicine in preventing chronic diseases and increasing patients’
survival rate.