Some Clinical Aspects of Uroflowmetry in Elderly Males. A Population Survey

Jensen, Karl Erik; Jørgensen, J.; Mogensen, Peter; Bille-Brahe, N. E.

doi:10.1016/s0022-5347(17)44244-3

Cited by 9 publications

(11 citation statements)

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“…Normal values for men have been deter mined as a function of age and voided volume [15][16][17][18][19][20], Maximum flow rates below 10 ml/s in men with symp toms of BPH are associated with obstruction [9,21], In a study of 64 men with clinically diagnosed BPH followed over 5 years, Ball and coworkers [22] found a decrease of 1.2 ml/s. This is in agreement with the value of 2.1 ml/s per decade found in a survey of normal men [17], While some statistically significant relationships between symp toms and maximum urinary flow rates have been ob tained, the correlations are weak and sensitivity and spec ificity are poor [10,23,24], Urinary flow rate alone can not be used to diagnose bladder outflow obstruction or to predict favorable response to prostatectomy [9,25,26], Most information on the clinical course of BPH has been obtained from relatively small series of patients fol lowed in urology clinics for symptoms of prostatism over various time periods [10,22,27], These studies have shown that the clinical course of BPH in individual patients is highly variable over time, whether measured by symptoms or by urinary flow rates. An appreciable fraction of patients improve spontaneously without treat ment.…”

Section: Pathogenesis and Anatomic Progressionsupporting

confidence: 90%

The Natural History of Benign Prostatic Hyperplasia: Implications for Patient Care and Clinical Trial Design

Guess¹

1994

Eur Urol

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Section: Pathogenesis and Anatomic Progressionsupporting

confidence: 90%

The Natural History of Benign Prostatic Hyperplasia: Implications for Patient Care and Clinical Trial Design

Guess¹

1994

Eur Urol

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“…Maximum flow rate has been shown to be significantly associated with symptom scores in some studies, 12,13 while other investigations have shown only weak correlations. 14,15 We searched a correlation between Q max , Q ave and ICS-BPH symptom score: a significantly inverse correlation was found only for Q max , confirming Q max as a reliable parameter to quantify subjective symptoms.…”

Section: Discussionmentioning

confidence: 86%

Home and office uroflowmetry for evaluation of LUTS from benign prostatic enlargement

Porru

Scarpa²,

Prezioso³

et al. 2005

Prostate Cancer Prostatic Dis

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A group of 107 patients with lower urinary tract symptoms (LUTS) from benign prostatic enlargement (BPE) participated to the HOUSE Study (Home and Office Uroflowmetry Specific Evaluation). Patients received routine investigation, consisting of medical history taking, physical examination including digital rectal examination, prostate-specific antigen (PSA), assessment of symptoms listed both on the International Prostate Symptom Score and on ICS-male questionnaire. We examined the results of uroflowmetry evaluation in this population; data were analysed to observe if any circadian changes of parameters obtained with home uroflowmetry could be detected. We searched a correlation between Q max , Q ave and ICS-benign prostatic hyperplasia symptom score: a significantly inverse correlation was found only for Q max , confirming Q max as a reliable parameter to quantify subjective symptoms. When examining the multiple flow curves recorded in the same patient with home uroflowmetry, voided volume and flow time had usually higher values during night-time: the existence of circadian changes of uroflowmetry parameters in patients with LUTS from BPE was confirmed, and lower values of average and maximum flow rates during sleep hours were recorded in the same patient. In conclusion, when evaluating the natural history or treatment outcome of individual patients or group of patients in clinical trials for evaluation of BPE and LUTS, an assessment including multiple measurements may be useful and of value.

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“…(3) talking to other patients, (4) ward group (regular meetings composed of patients and staff), (5) occupa-tional therapy, (6) drug treatment, (7) the ward round, (8) just being in hospital, (9) visitors, and (10) free pass (permission to leave the ward). The patients' estimate of the time engaged in these activities was noted.…”

Section: Patients Methods and Resultsmentioning

confidence: 99%