Spielen f�r die Ruheatmung des Menschen vom O2-Druck abh�ngige Erregungen der Chemoreceptoren eine Rolle?

Loeschcke, G. C.

doi:10.1007/bf00364363

Cited by 37 publications

(9 citation statements)

References 35 publications

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“…This supports the conclusions of Watt, Dumke and Comroe [1943] of Loeschcke [1953] and of Dejours, Labrousse, Raynaud and Teillac [1957]. The data of Lambertsen, Ewing, Kough, Gould and Stroud [1955] provide some support for our view that E (or D) has a finite value, i.e., that C02-sensitivity does not tend to zero as P02 tends to infinity.…”

Section: Resultssupporting

confidence: 85%

The Relation Between Alveolar Oxygen Pressure and the Respiratory Response to Carbon Dioxide in Man

Lloyd¹,

Jukes²,

Cunningham³

1958

Exp Physiol

230

110

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Section: Resultssupporting

confidence: 85%

The Relation Between Alveolar Oxygen Pressure and the Respiratory Response to Carbon Dioxide in Man

Lloyd¹,

Jukes²,

Cunningham³

1958

Exp Physiol

230

110

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“…Comparing the ventilation of 1 min of breathing 34 % oxygen with the previous minute of air breathing in our infants showed a mean fall of 8-1 % in REM sleep and 9 5 % in orthodox sleep, very close to the figures published by Loeschke (1953) for young adults. But this small change did not reach statistical significance because of the variability between the periods measured and inconsistency between babies.…”

Section: Discussionsupporting

confidence: 70%

Ventilation and sleep state in the new‐born

Bolton¹,

Herman²

1974

The Journal of Physiology

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SUMMARY1. Ventilation, oesophageal pressure and sleep state were measured in fourteen babies between 25 hr and 7 days of age.2. Trunk plethysmograph records showed that respiratory rate and minute volume were significantly higher in REM sleep than non-REM sleep. Tidal volume was not significantly altered.3. Tidal volume, respiratory rate and minute volume were all more variable in each baby in REM sleep, both on breath to breath analysis and over successive 20 sec periods.4. Major oesophageal peristaltic activity was observed in REM sleep only.5. In response to a sharp rise in Po2 the tidal volume and minute volume fell significantly by the same proportion in both sleep states. Respiratory rate did not change significantly.

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“…We also reasoned that sudden withdrawal of peripheral chemoreceptor drive would allow any central depressant effects of sustained isocapnic hypoxia to be better observed and compared between men and women. However, hyperoxia without preceding hypoxia has been shown to produce immediate short-term ventilatory depression (9,11,22). Recent studies have shown that ventilation increases during sustained hyperoxia (6,7).…”

Section: Ventilatory Changes After Sustained Isocapnic Hypoxiamentioning

confidence: 99%

Comparison of effects of sustained isocapnic hypoxia on ventilation in men and women

Sajkov

Neill

Saunders

et al. 1997

Journal of Applied Physiology

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Sleep-related respiratory disturbances are more common in men than in premenopausal women. This might, in part, be due to different susceptibilities to the respiratory depressant effects of hypoxia. Therefore, we compared ventilation during 10 min of baseline room-air breathing and 20-min sustained isocapnic hypoxia (fractional inspired O2 = 11%, arterial saturation of O2 approximately 80%) followed by 10 min of breathing 100% O2 in 10 normal men and in 10 women in the follicular phase of the menstrual cycle. Control measurements were made during two transitions from room air (10 min) to 100% O2 (10 min) and averaged. Inspired minute ventilation (VI) after 2 min of hypoxia was the same in men and women [131 +/- 6.1% baseline for men, 136 +/- 7.7% baseline for women; not significant (NS)] and declined to the same level after 20 min (115 +/- 5.0% baseline for men, 116 +/- 6.6% baseline for women; NS) associated with a similar decline in inspiratory time and tidal volume. Breathing frequency did not change. VI decreased transiently during subsequent 100% O2 breathing in both men and women, associated with reduced frequency and duty cycle and increased expiratory time. The fall in VI was significantly greater than that observed during control hyperoxia experiments in men but not in women. We conclude that ventilatory responses to sustained isocapnic hypoxia do not differ between awake healthy men and women in the follicular phase of their menstrual cycle. However, after termination of isocapnic hypoxia, men appear to depress their ventilation to a greater degree than women.

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Spielen f�r die Ruheatmung des Menschen vom O2-Druck abh�ngige Erregungen der Chemoreceptoren eine Rolle?

Cited by 37 publications

References 35 publications

The Relation Between Alveolar Oxygen Pressure and the Respiratory Response to Carbon Dioxide in Man

The Relation Between Alveolar Oxygen Pressure and the Respiratory Response to Carbon Dioxide in Man

Ventilation and sleep state in the new‐born

Comparison of effects of sustained isocapnic hypoxia on ventilation in men and women

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