Status of Serum Zinc and Magnesium among Type 2 Diabetic Subjects in Maiduguri

Mamza, Y. P.; Abdullahi, Z.; Gali, Rebecca Mtaku; Mshelia, DS; Genesis, R.Y.; Habu, Satoshi

doi:10.9790/0853-150716670

Cited by 7 publications

(10 citation statements)

References 28 publications

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“…Our results disagree with Zargar et al, [12], and Unjiati et al, [13], where they found no signifi cant change when compared with normal persons. Also our results disagree with Osman et al, [14], and Mumza et al, [15], where they found signifi cant change (increase) when compared with normal persons. [30,5,6).…”

Section: Resultscontrasting

confidence: 99%

“…In our study the FBS was negatively inverse correlated with serum concentration of zinc (r=-0.672, p <0.001) in uncontrolled diabetics which disagree with Mumza et al, [15],…”

Section: Resultscontrasting

confidence: 99%

“…Anderson et al, [5] reported that 30% patients with DM found to be zinc defi cient. There are different data regarding Zn level in diabetic patients where some authors (large number) stated that Zn is defi cient in diabetics [5,11], others found no change [12,13], others found an increase in Zn concentration [14,15].…”

Section: Introductionmentioning

confidence: 99%

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Serum/Urine Zn Level of Egyptian Type II Diabetic Patients and Its relation with Glycemic Control (HbA1c)

Soliman¹

2019

J Biol Med

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Introduction: Diabetes Mellitus is a metabolic disorder disease characterized by hyperglycemia due to impaired insulin secretion or action. Percent of Type 2 diabetic patients are getting to increase annually allover the world especially in developing countries. It is estimated to increase to 300 million in 2025. In Egypt around 8.1 million are estimated according to IDF 2015. Zinc is a trace element that acts as cofactor for synthesis, storage, stability and secretion of insulin by pancreas. There is a controversy studies regarding Levels of trace elements as Zinc in diabetic patients. Aim: To assess the level of zinc in Egyptian type 2 diabetic patients and its relation to glycemic control. Material and methods: One hundred and twenty type 2 diabetic patients, with duration of diabetes > 2 years, age 30-45 year; and 60 age and sex matched; healthy normal controls receiving oral antidiabetic drugs were included in this study. Serum Zn, Fasting blood sugar (FBS) and HbA1c levels were estimated. Diabetic patients were divided into 2 groups, 60 diabetics /group: controlled diabetics (HbA1c < 7); and uncontrolled diabetics (HbA1c > 7). Results: Serum Zn levels of uncontrolled diabetics were signifi cantly lower (56.18 ± 0.66 μg/dl) than controlled diabetic (76.61 ± 2.44) and normal controls (84.30 ± 0.98 μg/dl, p < 0.001). An inverse signifi cant correlation with found between serum concentration of zinc and FBS; and HbA1c in uncontrolled diabetics. Conclusion: Altered levels of trace elements as Zn are found to be important predisposing factors for diabetic patients.

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Section: Resultscontrasting

confidence: 99%

“…In our study the FBS was negatively inverse correlated with serum concentration of zinc (r=-0.672, p <0.001) in uncontrolled diabetics which disagree with Mumza et al, [15],…”

Section: Resultscontrasting

confidence: 99%

See 1 more Smart Citation

Serum/Urine Zn Level of Egyptian Type II Diabetic Patients and Its relation with Glycemic Control (HbA1c)

Soliman¹

2019

J Biol Med

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“…Zinc is required for insulin synthesis and storage and insulin is secreted as zinc crystals. It maintains the structural integrity of insulin 21 . Zinc deficiency may play a role in the pathogenesis of polycystic ovarian syndrome and may be related with its long-term metabolic complications 22 .…”

Section: Introductionmentioning

confidence: 99%

Study of Trace Elements Selenium, Copper, Zinc and Manganese Level in Polycystic Ovary Syndrome (PCOS)

Mohmmed¹,

Awad²,

Al–Fartosy³

2019

IJRASB

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women, trace elements play an important role in PCOS, selenium performs various biological functions such as defense against oxidative stress, immune function and thyroid function, polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women, trace Elements have important role in PCOS, selenium is involved in many biological functions, such as, protection against oxidative stress, immune function and thyroid function, Copper, zinc and manganese are essential micronutrients that have been integrated into various proteins and metalloenzymes and are active in the metabolic process of cells and in oxidative stress pathways that can lead to oxidative stress. One hundred and twenty-four of patients' women with poly cystic ovarian syndrome (PCOS) patients and 56 normal ovulatory women participated in the study. Seleniumand serum Copper, zinc and manganese were measured by using flame atomic absorption spectrometry (FAAS).

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“…8 On the contrary, Mumza et al reported high zinc level in type 2 DM patients. 9 Therefore, this study was conducted to determine the serum zinc status and its relationship with age, gender, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood sugar (FBS), glycosylated hemoglobin (HbA1C) and lipid levels in type 2 DM patients.…”

Section: Introductionmentioning

confidence: 99%