The utilization of plant-based pesticides and the selection of cultivars of cayenne pepper have not been well optimized by farmers. The purpose of the study was to analyze the types of cayenne pepper pests, examine the association of cayenne cultivars against pest attacks, and analyze the application of commercial vegetable pesticides to pest visits. The research method used was experimental with a completely randomized design. The sample of this study consisted of three cayenne cultivars, namely Sret, Mhanu XR, and Green Chakra. The research instrument used observation sheets of pest communities before and after the application of vegetable pesticides. The type and number of pests are directly observed and identified in the laboratory. Data on the influence of cayenne cultivar on pest populations were analyzed by ANOVA test while the effect of using vegetable pesticides using t-test. The results showed that the types of pests found were Aphis sp., Polyphagotarsonemus sp., Thrips sp., Bactrocera sp. and Chrysodeixis sp. Statistical tests showed cayenne cultivar did not significantly influence pest visits while the application of plant-based pesticides had a significant effect on the decrease in Thrips sp. and Aphis sp. The conclusion of this study, namely five types of pests attack three cayenne cultivars, the selection of three chili cultivars does not affect pest visits while the application of vegetable pesticides can reduce the number of pest visits Thrips sp. and Aphis sp significantly.