Studies on Nutrition and Avian Malaria: IV. Protein Deficiency

Influence of Nutrition in Experimental Infection

“…These results were soon confirmed (42). A deficiency in folio acid (43) or in protein (44), also decreases the resistance of chickens to P. lophurae. Since folio acid deficiency in chickens is accompanied by anemia as well as leucopenia, the higher relative parasite counts observed may have been partly due to the smaller number of red cells.…”

“…Protein deficiency which, as Cannon (49) has shown, lowers the ability to produce antibodies, had no effect on the resistance of the albino rat to Trypanrosoma lewiai (40). Extreme protein deficiency, of the type which reduces the resistance of chicks to Pktemodium lophurae (44), might well interfere with many mechanisms other than those concerned with the synthesis of antibody gamma globulins.…”

Influence of Nutrition in Experimental Infection1

“…Protein deficiency which, as Cannon (49) has shown, lowers the ability to produce antibodies, had no effect on the resistance of the albino rat to Trypanrosoma lewiai (40). Extreme protein deficiency, of the type which reduces the resistance of chicks to Pktemodium lophurae (44), might well interfere with many mechanisms other than those concerned with the synthesis of antibody gamma globulins. Becker and Gallagher (38) have suggested that pantothenic acid deficiency or the administration of salicylates reduces the resistance of rats to Trypanosoma l18 because they prevent the utilization of pantothenic acid as a coenzyme in the formation of a specific oxidative enzyme which inhibits the reproduction of the parasite.…”