Study of antimicrobial resistance due to extended spectrum betalactamase-producing Escherichia coli in healthy broilers of Jabalpur

Abstract

Aim:To study the prevalence of antimicrobial resistance due to extended spectrum beta-lactamase (ESBL)-producing Escherichia coli in samples collected from the ceca of healthy broilers of poultry sale outlets (PSOs) Jabalpur.Materials and Methods:A total of 400 cecal swab samples were taken randomly from freshly slaughtered poultry of 39 PSOs located at four different zones or areas of Jabalpur and were screened for the presence of ESBL-producing E. coli using standard methods. Further they were characterized phenotypically by standard methods.Results:All the 400 samples were screened for E. coli producing ESBL enzyme. Among the samples positive for E. coli 135 were positive for ESBL E. coli giving an overall prevalence of 33.5%.Conclusion:This study related to the prevalence of ESBL-producing E. coli in healthy broilers in Jabalpur is indicative of antibiotic resistance prevalent in the healthy birds which are used for human consumption as well. It also signifies resistance prevalent against beta-lactam antibiotics including third and fourth generations of cephalosporins.

A One Health Comparative Assessment of Antimicrobial Resistance in Generic and Extended-Spectrum Cephalosporin-Resistant Escherichia coli from Beef Production, Sewage and Clinical Settings

“…The generally high levels of AMR in ESC r as opposed to generic E. coli is a potential reflection of the enrichment procedure selecting for ESC r . Genes such as bla SHV , bla TEM and bla CTX-M are often borne on mobile genetic elements that code for resistance to multiple antimicrobials [ 54 , 55 , 56 ]. Although enrichment for ESC r was expected to only isolate β-lactamase resistant E. coli , 4.1% of isolates were susceptible to ampicillin.…”

Prevalence of extended-spectrum beta-lactamase producing bacteria from animal origin: A systematic review and meta-analysis report from India

“…A high prevalence of ESBL-producing E . coli in pig and cattle farms emphasizes the fact that livestock animals are a constant source for these potential human pathogens [33, 40–41].…”

Susceptibility to disinfectants in antimicrobial-resistant and -susceptible isolates of Escherichia coli, Enterococcus faecalis and Enterococcus faecium from poultry-ESBL/AmpC-phenotype of E. coli is not associated with resistance to a quaternary ammonium

“…); it has been assumed that reduced susceptibility to disinfectants might be one factor currently associated with the high prevalence of ESBL‐producing strains in poultry (Shrivastav et al . ). Thus, we particularly looked into the performance of the investigated disinfectants in ESBL/AmpC (hyper‐)producing E. coli .…”