Synthese der homologen Reihen der Alkyl‐phenyl‐ketone und der d,l‐Alkyl‐phenyl‐carbinole (XII. Mitteil.) über isomere und homologe Reihen

Abstract

Nr. 9/1954] B r e u s c h , O g u z e r 1225 -_ .. durch Schmelzpunkt und Mischschmelzpunkt identihiert, die Phenylessigsiiure durch nerfuhren in das Amid vom Schmp. 156'. Der Rest siedete bei 200-2100/0.1 Ton. Das Destillat erstante, ohne jedoch richtig zu kristallisieren. Oberfuhren der Siiure in das Amid ergab eine schon kriatallisierte Verbindung vom Schmp. 133O (aus w a r . Athanol), die mit dem Amid der or,P-Diphenyl-propionsaureg) identich ist. C,,H,,ON (225.3) Ber. C80.00 H 6.22 N6.22 Gef. C79.96 H6.44 N6.00 U m s e t z u n g d e s M e t h y l -b u t y l -a c e t y l e n s m i t Peressigsaure: 2 0 g Methylb u t y l -a c e t y l e n wurden analog dem Dibutyl-acetylen mit Peressigsaure umgesetzt. Die Destillation ergab zwei Raktionen. Nach der Valeriansiiure (Sdp.,, 87O) ging cz-Methyl-capronsliure uber; Sdp.,, 110-1120, nij 1.4200, d1'= 0.9085. Die Saure bildete mit Harnstoff kein Addukt.C,Hl,O, (130.2) Ber.

Synthesis of New Chiral and Racemic 1,3‐Dioxolanes

“…In the first step of our study, five prochiral alkyl phenyl ketones 1a , 1b , 1c , 1d , 1e were synthesized via Friedel Crafts reaction (Scheme ) . Two of them ( 1d and 1e ) were obtained for the first time in this study.…”

Synthesis and antioxidant activities of novel N‐aryl (and N‐alkyl) γ‐ and δ‐imino esters and ketimines

“…The chemicals used in this study were commercially available from Merck, Aldrich, and Across Organics, and used without further purification. The γ‐ and δ‐keto esters and long‐carbon‐chain ketones as starting materials were synthesized by Friedel–Crafts acylation . 5‐Oxo‐5‐phenyl‐pentanoic acid purchased from Acros Organics was converted to the methyl ester by an esterification reagent.…”

Synthesis, characterization, and evaluation of antioxidant activity of new - and -imino esters

“…Friedel-Crafts acylation was used to synthesize γ -and δ -keto esters. 23,24 The starting compounds and imines were purified by column chromatography on silica gel (particle sizes 0.063-0.200 mm and 0.040-0.063 mm, respectively). 1…”