Synthesis and Characterization of Diphenyltin(IV) Dicarboxylates Containing Germanium

Abstract

have been synthesized by the reaction of diphenyltin oxide with a germanium substituted propionic acid. All the compounds were characterized by elemental analysis, IR, multinuclear ( 1 H, 13 C, 119 Sn) NMR and Mössbauer spectroscopies as well as mass spectrometry. The in vitro antibacterial activity of selected compounds is also reported.

Synthesis, structural elucidation, and biological activity to organotin(IV) derivatives of (E)‐2,3‐bis(4‐chlorophenyl)‐2‐propenoic acid

“…Keeping theses aspects under consideration, in continuation to our previous work, we report here the synthesis and characterization of organotin(IV) derivatives of ( E )‐2,3‐bis(4‐chlorophenyl)‐2‐propenoic acid and their antibacterial, antifungal, and cytotoxicity studies. Cinnamic acid is a naturally occurring unsaturated carboxylic acid that has low toxicity and a broad spectrum of biological activities.…”

“…The IR data play an important role in characterizing organotin(IV) carboxylates. There are two important ways of characterizing organotin(IV) carboxylates: firstly by comparison with that of precursors and then with that of the reported data, and secondly, verification of functional group presence . The coordination of carboxylate group is decided on the basis of the Δν[ν(OCO) asym‐ ν(OCO) sym ] in organotin compounds .…”

“…The characteristic resonance peaks in the 1 H NMR spectra of compounds 1‐8, and free ligand is given in experimental part. The spectra were assigned on the basis of peak intensity, multiplicities, and comparison with the literature values reported earlier …”

Synthesis, characterization, and biological effects of diorganotin(IV) derivatives of substituted germyl propionic acid and crystal structure of 3‐triphenylgermyl‐3‐P‐fluorophenyl propionic acid

“…Syntheses of the complexes were prepared by procedures cited in the literature [5][6][7][8]. The physical properties and melting points are given in Table 1.…”

“…For example, Silatorque [4] [(PhMe 2 SiCH 2 ) 3 Sn] 2 O has high-acaricidal activity but low toxicity toward other organisms. In a continuation of our previous work [5][6][7][8], we report here the synthesis and biological studies of several diorganotin(IV) derivatives containing a germanium moiety as a part of the carboxylate ligand.…”