Synthesis and spectral characterization of silver/magnesium co-substituted hydroxyapatite for biomedical applications

Synthesis, characterization, in vitro bioactivity and antimicrobial activity of magnesium and nickel doped silicate hydroxyapatite

“…Antibacterial properties of Ni 2 þ doped Mg-SiHA samples were investigated qualitatively and quantitatively against P. aeruginosa, and E.coli, respectively. Results showed that HA, SiHA, and Mg-SiHA had no effect on the growth of P. aeruginosa, and E.coli, which is consistent with previous studies conducted on different types of microorganism [60][61][62][63], however incorporation of Ni 2 þ played a vital role in increased activity of Mg-SiHA against microorganism.…”

Cationic and Anionic Substitutions in Hydroxyapatite

“…The produced systems include the co-substitution of zinc/silver [209], silver/strontium [211], carbonate/strontium [492], carbonate/magnesium [454,493], carbonate/sodium [494], carbonate/silicate [495], yttrium/silicon [496], zinc/silicate [497], zinc/copper [498], strontium/cerium [499], magnesium/ strontium [500], magnesium/silver [501], and carbonate/silicate/magnesium [454]. However, the co-substitution of multiple (more than two) ions has not deeply and systematically attempted and investigated, and thus, it can be considered as a promising research field to be still and further explored and expanded [502,480].…”

Antibacterial efficacy, corrosion resistance, and cytotoxicity studies of copper-substituted carbonated hydroxyapatite coating on titanium substrate

“…, and Zn 2? ) is more appropriate because they show antimicrobial activity at the site of implant materials and they are not cytotoxic at low concentrations [9][10][11][12]. Besides its antimicrobial activity, Cu is an essential trace element for mammalian life [10,13], and it stimulates the activity of several enzymes and plays a role in the crosslinking of collagen and elastin of bones [10,14].…”