Synthesized mesoporous silica and calcium aluminate cement fillers increased the fluoride recharge and lactic acid neutralizing ability of a resin-based pit and fissure sealant

Abstract

This study evaluated the effect of different types of filler in a resin-based pit and fissure sealant on fluoride release, recharge, and lactic acid neutralization. Resin-based sealant was incorporated with 5% w/w of the following fillers: calcium aluminate cement (CAC), synthesized mesoporous silica (SI), a CAC and SI mixture (CAC+SI), glass-ionomer powder (GIC), and acetic acid-treated GIC (GICA). Sealant without filler served as control. The samples were immersed in deionized water or a lactic acid solution and the concentration of fluoride in the water, before and after fluoride recharge, and the lactic acid pH change, respectively, were determined. The CAC+SI group demonstrated the highest fluoride release after being recharged with fluoride gel. The CAC+SI group also demonstrated increased lactic acid pH. These findings suggest that a resin-based sealant containing synthesized mesoporous silica and calcium aluminate cement may enhance remineralization due to fluoride release and higher pH.

The Fluoride Ion Release from Ion-Releasing Dental Materials after Surface Loading by Topical Treatment with Sodium Fluoride Gel

“…The restorative material can store fluoride ions when exposed to a medium enriched with fluoride ions after previously releasing a certain number of ions from its structure [ 2 ]. The material structure, the product type, and the concentration of fluoride ions to which the material is exposed are factors that determine the number of fluoride ions that the material can receive [ 3 , 4 , 5 , 6 ]. Ion-releasing restorative materials have a relatively well-explored fluoride release time [ 7 ]; hence, the question of interest is whether the recharge process may be clinically relevant as the material genuine fluoride release.…”

“…The permeability, composition, porosity, and surface retention of ions in dental restorative materials affect the recharge capacity [ 3 , 8 , 9 , 10 ]. More permeable materials can store fluoride ions deeper in their structure, whereas impermeable materials adsorb ions mainly on their surface [ 11 ].…”

“…However, there are findings of some materials without prior ion release capability that were able to release more ions after the recharge protocol compared to some glass-ionomer materials [ 3 ]. Although previous studies indicated the superiority of glass-ionomer cements in terms of rechargeability compared to giomer materials, according to Rai et al [ 19 ], newer materials such as the “alkasite” composite show the ability to release more fluoride ions than glass-ionomer cement.…”

Microwave-Assisted Fabrication of Mesoporous Silica-Calcium Phosphate Composites for Dental Application

“…In this work, we obtained mesoporous silica-calcium phosphate composites using a simple microwave-assisted wet precipitation method. For this purpose, mesoporous silica SBA-15 was chosen as an initial material due to its confirmed application potential in dentistry (resins-reinforcing agent [18] and cytocompatible filler [44], tooth remineralization enhancing agent [45], drug carrier [46]). The obtained SBA-15 material was next suspended in rapid coating solutions dedicated to hydroxyapatite precipitation that were selected based on a literature review.…”

Development of nanohybrid dental composite containing mesoporous carrier silica particles: Synthesis particles, determination of fluoride adsorption capacities, and addition of the composite

“…Bisphenol-A glycidyl methacrylate (BISGMA) is preferred as the main monomer of the organic matrix due to its high reactivity. [11,12] Strong intermolecular interactions caused by hydroxyl groups and the slowing down due to rotational movement of the phenolic groups in BISGMA result in high viscosity and a conversion rate of less than 42%. Low-viscosity triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) monomers are added to the composite formulations to increase the conversion degree of BISGMA and to ensure that it is filled with a large amount of particles.…”