Terramycin. Vii. The Structure of Terramycin

Hochstein, F. A.; Stephens, Charles R.; Conover, L. H.; Regna, Peter P.; Pasternack, Robert F.; Brunings, K. J.; Woodward, R. B.

doi:10.1021/ja01134a522

Cited by 44 publications

(17 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The structure of chlortetracycline was first resolved by the Woodward group in 1953 (Hochstein et al, 1953) (Figure 1). TET has linearly fused tetra cyclic rings as their backbone (which are heavily substituted) and a unique C2 amide group.…”

Section: Structurementioning

confidence: 99%

See 1 more Smart Citation

A Review on the Adsorption Studies of Tetracycline onto Various Types of Adsorbents

Priya

Radha

2017

Chemical Engineering Communications

View full text Add to dashboard Cite

Over the past few decades, the usage of antibiotics is growing on a rapid phase. The continuous use in the treatment against several bacterial infections paves a way to increased resistant strains. Environmental pollution created by antibiotics is considered as a serious problem though no toxic reports were known until now. The pharmaceutical compounds present in the environment are known as "Emerging Pollutants." Among antibiotics tetracycline (TET) class of drugs were known to exist for several years.Within 3-4 years of the discovery of the first class of TET, the resistant strains were also identified. TET usage is not only limited for human therapy but also greatly used in veterinary and agricultural purposes. These compounds have been detected in the environment, especially in aquatic farms, groundwater, surface water, etc., thus, it becomes vital to take some measures in removing these compounds from the ecosystem to some extent. Many degradation methodologies, mechanisms were applied to remove TET but were highly limited to synthetic effluents. Adsorption is a common practice at the industrial level, especially in effluent treatment processes. In this study, removal of TET through adsorption using various adsorbent was reviewed extensively.

show abstract

Section: Structurementioning

confidence: 99%

“…Backbone structure of tetracycline(Hochstein et al, 1953) Natural and semi-synthetic forms of tetracycline(Chopra and Roberts, 2001) An estimate of the amounts of different antibiotics used in medicine…”

mentioning

confidence: 99%

A Review on the Adsorption Studies of Tetracycline onto Various Types of Adsorbents

Priya

Radha

2017

Chemical Engineering Communications

View full text Add to dashboard Cite

show abstract

“…Oxytetracycline (OTQ, a broad-spectrum antibiotic produced by Streptomyces rimosus, is a bacteriostatic compound against both gram-positive and gram-negative microorganisms (Hochstein et al 1953). Since its isolation and development in 1950, OTC has become one of the most commonly used antibiotics in aquaculture.…”

mentioning

confidence: 99%

Oxytetracycline Residue in Striped Bass Muscle

Rogers

1994

Journal of Aquatic Animal Health

View full text Add to dashboard Cite

Tissue residues were measured in striped bass Morone saxatilis that had been injected intraperitoneally with 50 mg Oxytetracycline (OTQ/kg or had been fed a ration containing 75 mg OTC/kg of fish daily for 10 d. Concentration of OTC in muscle of fish fed medicated feed was below the quantitation limit in 67% of the fish 12 d after treatment and was below the quantitation limit in all fish after 16 d at 23°C. The calculated terminal elimination rate constant (ft) was 0.20/d (range, 0.15-0.37/d), and the half-life was 2.7 d (range, 1.9-4.5 d). The concentration of OTC in muscle after intraperitoneal injection was below the quantitation limit after 24 d at 23°C. The 0-value was 0.34/d and half-life was 2.0 d in fish injected with OTC intraperitoneally.

show abstract

“…Thanks to a collaboration with Robert B. Woodward , the structure of terramycin ( 11 )-isolated in the laboratories of "Chas. Pfi zer and Co." in 1950-was resolved ( 148 ).…”

Section: Volume 21mentioning

confidence: 99%

The Series “Progress in the Chemistry of Organic Natural Products”: 75 Years of Service in the Development of Natural Product Chemistry

Soukup

2014

Progress in the Chemistry of Organic Natural Products 100

View full text Add to dashboard Cite

Terramycin. Vii. The Structure of Terramycin

Cited by 44 publications

References 0 publications

A Review on the Adsorption Studies of Tetracycline onto Various Types of Adsorbents

A Review on the Adsorption Studies of Tetracycline onto Various Types of Adsorbents

Oxytetracycline Residue in Striped Bass Muscle

The Series “Progress in the Chemistry of Organic Natural Products”: 75 Years of Service in the Development of Natural Product Chemistry

Contact Info

Product

Resources

About