1919
DOI: 10.1016/s0021-9258(18)87274-x
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The Action of Intravenous Injections of Pancreas Emulsions in Experimental Diabetes

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Cited by 61 publications
(11 citation statements)
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“…7], and others) to isolate a pancreatic, glucose-lowering factor (8)(9)(10). Indeed, between 1915 and 1919, Kleiner and Meltzer at the Rockefeller University published promising glucose-lowering results of their pancreatic extracts in depancreatized dogs (11,12). Furthermore, a Romanian scientist, Nicolas Paulesco, published a series of important papers in 1921 describing successful experimentation with pancreatic extracts, which he called "pancréine" (13)(14)(15)(16)(17).…”
Section: The Toronto Researchers' Breakthrough In Isolating Insulinmentioning
confidence: 99%
“…7], and others) to isolate a pancreatic, glucose-lowering factor (8)(9)(10). Indeed, between 1915 and 1919, Kleiner and Meltzer at the Rockefeller University published promising glucose-lowering results of their pancreatic extracts in depancreatized dogs (11,12). Furthermore, a Romanian scientist, Nicolas Paulesco, published a series of important papers in 1921 describing successful experimentation with pancreatic extracts, which he called "pancréine" (13)(14)(15)(16)(17).…”
Section: The Toronto Researchers' Breakthrough In Isolating Insulinmentioning
confidence: 99%
“…Hay quienes dicen que este francés tenía poca confianza en sus investigaciones. También trabajaron en el tema los norteamericanos Israel Kleiner, Ernest Scott y John Murlin y Benjamin Kramer (10)(11)(12).…”
Section: Comprobando La Hipótesis De La Insulinaunclassified
“…Israel Kleiner (1885–1966) carried out similar experiments on diabetic dogs in New York 18 . Injections of unfiltered water extracts of fresh pancreas diluted in 0.9% saline resulted in a marked decrease in blood sugar levels.…”
Section: The Introduction Of Pancreatic Extractsmentioning
confidence: 99%