The paper presents the results of the study of the parameters of the highly sensitive active medium of the NO2 sensor based on a cholesterol-nematic mixture with an admixture of carbon nanotubes. The dependence of the change in the wavelength of the two transmission minima on the NO2 concentration for cholesterol-nematic mixture with single-walled, double-walled and multi-walled nanotubes at different concentrations of nanotubes and two concentrations of nematically liquid crystal 5CB were obtained. It is established that by changing the ratio between the concentrations of nanotubes and nematic liquid crystals, it is possible to obtain mixtures that have the maximum spectral sensitivity coefficient in a given range of gas concentration.