The Effect of Hypnosis on the Intensity of Pain and Anxiety in Cancer Patients: A Systematic Review of Controlled Experimental Trials

Sine, Hayat; Achbani, Abderrahmane; Filali, K

doi:10.1080/07357907.2021.1998520

Cited by 15 publications

(5 citation statements)

References 74 publications

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“…Therefore, recently there has been a clear tendency in pain medicine toward comprehensive pain management involving also non-pharmacological options (29, 30). Importantly, as shown by a number of recent systematic reviews and metaanalyses, some non-pharmacological treatments can be effective also in patients with cancer pain (31)(32)(33)(34)(35). Therefore, we included to our study clinical trials of non-pharmacological interventions alongside those evaluating the effects of analgesic drugs.…”

Section: Discussionmentioning

confidence: 99%

Exclusion of older adults from clinical trials in cancer-related pain

et al. 2022

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Pain is one of the most common symptoms in cancer patients including older adults. The objective of this study was to evaluate the enrollment criteria that can limit the inclusion of older adults in clinical trials concerning cancer-related pain (CRP). The study included 356 trials registered with ClinicalTrials.gov. Our primary outcome measures were the proportion of trials that excluded patients based on upper age limits (80 years of age or less), strict organ-specific exclusion criteria, broad and imprecise criteria, and inadequate performance score. One hundred and twenty-six trials (35.4%) had upper age limits. Strict exclusion criteria were used in 95 (26.7%) trials. Broad and imprecise exclusion criteria were listed in 57 (16.2%) trials. Low performance score was used as an exclusion criterion in 4 trials (1.1%). Overall, in 241 trials (67.7%) there was either an upper age limit or at least one strict or broad and imprecise exclusion criterion, or a criterion involving the performance status. The odds of excluding older adults were significantly higher in certain neoplasm types, study objectives, intervention types, and center locations. In conclusion, considerable proportion of recent clinical trials concerning CRP either explicitly exclude older adults or create high risk of such exclusion which substantially limits the evidence base for the treatment of such patients in clinical practice. Sponsors and investigators should consider careful modification of the enrollment criteria to improve the inclusion of older individuals who make up the major proportion of cancer patients population.

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Section: Discussionmentioning

confidence: 99%

Exclusion of older adults from clinical trials in cancer-related pain

et al. 2022

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“…Hypnosis demonstrates clinical utility across diverse chronic pain conditions including low back pain, arthritis, fibromyalgia, migraine, cancer pain, and more [181][182][183][184][185] (Additional file 1: Fig. S2).…”

Section: Hypnosismentioning

confidence: 99%

Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress

Shi,

2023

BMC Med

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Background Chronic pain conditions impose significant burdens worldwide. Pharmacological treatments like opioids have limitations. Non-invasive non-pharmacological therapies (NINPT) encompass diverse interventions including physical, psychological, complementary and alternative approaches, and other innovative techniques that provide analgesic options for chronic pain without medications. Main body This review elucidates the mechanisms of major NINPT modalities and synthesizes evidence for their clinical potential across chronic pain populations. NINPT leverages peripheral, spinal, and supraspinal mechanisms to restore normal pain processing and limit central sensitization. However, heterogeneity in treatment protocols and individual responses warrants optimization through precision medicine approaches. Conclusion Future adoption of NINPT requires addressing limitations in standardization and accessibility as well as synergistic combination with emerging therapies. Overall, this review highlights the promise of NINPT as a valuable complementary option ready for integration into contemporary pain medicine paradigms to improve patient care and outcomes.

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“…Numerous studies have revealed that hypnosis is a nonpharmacological and cost-effective method that can be used as an effective and safe method for the management of diverse conditions, such as pain, anxiety, mood disorders, sleep problems, depression and anxiety, wound healing, haemorrhage, stress and pain associated with medical and surgical procedures, and gastrointestinal disorders [ 9 , [157] , [158] , [159] , [160] , [161] , [162] , [163] , [164] , [165] , [166] , [167] , [168] , [169] , [170] , [171] , [172] , [173] , [174] ].…”

Section: Hypnosismentioning

confidence: 99%