2019
DOI: 10.1186/s42358-019-0074-8
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The effect of therapies on the quality of life of patients with systemic lupus erythematosus: a meta-analysis of randomized trials

Abstract: Introduction: Systemic lupus erythematosus (SLE) is a multi-systemic, chronic inflammatory disease of autoimmune nature, which can impair performance in daily life activities, causing to a compromised quality of life. Thus, the aim of this study was to evaluate the effect of therapies, such as physical activity, cognitive behavioral therapy, pharmacological treatment and phytotherapy in the quality of life of patients with systemic lupus erythematosus. Materials and methods: A systematic review with a meta-ana… Show more

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Cited by 23 publications
(15 citation statements)
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“…29 Another possible intervention is cognitivebehavioural therapy as it has been shown to improve physical, social and mental function, while also lowering levels of depression and anxiety in SLE patients. 30,31 Patient-oriented research is essential to design new strategies for the management of lupus patients. 32 Some of the limitations of this study include its crosssectional design, which minimizes the causal inferences that can be made regarding psychological variables and the perception of sexual function.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…29 Another possible intervention is cognitivebehavioural therapy as it has been shown to improve physical, social and mental function, while also lowering levels of depression and anxiety in SLE patients. 30,31 Patient-oriented research is essential to design new strategies for the management of lupus patients. 32 Some of the limitations of this study include its crosssectional design, which minimizes the causal inferences that can be made regarding psychological variables and the perception of sexual function.…”
Section: Discussionmentioning
confidence: 99%
“…29 Another possible intervention is cognitive-behavioural therapy as it has been shown to improve physical, social and mental function, while also lowering levels of depression and anxiety in SLE patients. 30,31 Patient-oriented research is essential to design new strategies for the management of lupus patients. 32…”
Section: Discussionmentioning
confidence: 99%
“…Mesmo que as taxas de sobrevida de indivíduos com LES venham apresentando aumento significativo nos últimos anos, (18) isto não necessariamente tem impactado na QVRS, (13,16,19,20) pois a mesma é influenciada por manifestações da doença decorrentes do processo de adoecimento. Destarte, o LES é uma doença incurável de evolução não uniforme, sendo comum a existência de períodos de exacerbação e remissão, (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) levando ao comprometimento da vida cotidiana, a recorrentes internações hospitalares e, consequentemente, a uma baixa QVRS.…”
Section: Discussionunclassified
“…(7,8) Além dos sintomas específicos, a presença frequente da dor tem sido relacionada aos níveis de fadiga, ansiedade e depressão, (8) que associados a outros sintomas acabam por comprometer o cotidiano e a qualidade de vida relacionada à saúde (QVRS). (9) Além disso, o adoecimento por LES pode desenvolver complicações como a doença renal crônica, dano vascular, aterosclerose, dentre outras. (10) Marcadas por limitações físicas e psicológicas significativas, que também impactam na condição física, psíquica e social do individuo e consequentemente em sua QVRS.…”
Section: Introductionunclassified
“…In SLE specifically, despite the paucity of data, mindful-based interventions, such as cognitive behavioral therapy, have been shown to improve pain, 46 physical functioning, 46 stress, 47 anxiety, 47,48 and quality of life. 4951 Moreover, aerobic exercise has been shown to improve fatigue, 26,5257 depression, 52 and anxiety 57 in SLE. With increasing evidence emphasizing the importance of reduction in stress in addition to the multidimensional benefits of exercise, it stands to reason that regular physical activity be incorporated into standard daily clinical practice.…”
Section: Introductionmentioning
confidence: 99%