Important factors in grouper mariculture are continuous availability of seeds. Purpose of this research was to analyse production performance and financial analysis of three segments that support production of cantang hybrid grouper (macan/tiger, Epinephelus fuscoguttatus × kertang/giant, Epinephelus lanceolatus) and cantik hybrid grouper (macan/tiger, Epinephelus fuscoguttatus × batik/camouflage, Epinephelus microdon). Research was conducted for one year in 2022 three businesses, namely egg production, small-scale hatchery and nursery businesses. Egg production in a year for cantang hybrid grouper 97,300,000 eggs and cantik hybrid gouper of 17,800,000 eggs. Small-scale hatchery were harvested with average total length of ± 3.0 cm with SR 2.1–15.7% for cantang and 4.3–18.2% for cantik. Nursery were harvested with average total length of cantang seeds was 10.9 ± 0.3 cm with SR of 60.2–84.5% and seeds was 10.1 ± 0.3 cm with SR of 74.9–91.8%. Egg production obtained profit IDR 444,144,168/year, R/C ratio 1.67, and payback period 1.16 year. Egg production business in 5 years obtained NPV IDR 834,544,410, net B/C 2.63, and IRR 78.90%. Small-scale hatchery business profit IDR 414,508,032/year, R/C ratio 1.94, and payback period 1.40 year with NPV IDR 783,041,394, net B/C 2.35, and IRR 65.10%. Nursery business profit IDR 524,700,000/year, R/C ratio 1.73, and payback period 1.17 year with NPV IDR 1,097,840,171, net B/C 2.78, and IRR 79.30%. Sensitivity analysis shows that increases and decreases that occur in amount of production and selling prices have significant effect on NPV value. In addition, increase in profitability performance is associated with decrease in broodstock, eggs, seeds, feeds, or labor costs.