This study aims to determine the effectiveness of the entrepreneurship subject learning program at Purworejo State Vocational School in 2019/2020. The research uses an evaluation research approach (evaluation research). The evaluation model used is the EKOP model (Evaluation of Learning Quality and Learning Output). The population of all State Vocational Schools in Purworejo Regency is 7 State Vocational Schools. The sample amounted to 2 SMK, namely SMKN 2 and SMKN 3. Each SMK was taken two majors as samples. Sampling using cluster random sampling. From the four majors obtained a sample of 299 students as respondents. The data collection method used a questionnaire with a rating scale of 4 and document analysis. Data analysis used descriptive analysis. The results of the teacher performance evaluation average score = 3.22 with a classification of "good", the average score of learning facilities = 3.26 with a classification of "very good", class climate average score = 3.02 with a classification of "good", student attitudes average score = 3.12 with a "good" classification, learning motivation average score = 3.01 with a "good" classification, entrepreneurial interest average score = 3.22 with a "good" classification, and academic skills from the end-semester assessment average score = 2.82 for the scale and 82.29 for the scale of 100 with a classification of "good". The quality of learning with a mean total score = 3.13, classification "good". While the learning output with a mean total score = 3.02 with a classification of "good". The average learning program evaluation score = 3.07 "good" qualification. Based on these results, it can be concluded that the entrepreneurship learning program at Purworejo State Vocational School in 2019/2020 has been going well.