The integration of entrepreneurship value education can deliver creative and innovative Indonesian people, is a necessity, urgent in terms of necessity/regulation and the demands of community needs. Law-No.20/2003/National Education System, implies that education is carried out in a democratic, non-discriminatory manner, Human Rights are upheld, cultural/cultural values, religion, and national diversity are respected. The implementation is expected by the community. Assessed through literature studies, the data comes from books/documentation, journal writing, relevant media and is still feasible. The data obtained is compiled, analyzed, and concluded so as to get conclusions about the problem under study. The results of the study show that; The management of the integration of entrepreneurship education can give a person freedom to self-actualization, in the end it will create creative and innovative Indonesian people based on the cultural, religious, and pluralistic values of the Indonesian people. Consistency The implementation of management in integrating entrepreneurial values will be useful in facing the challenges of the industrial revolution 4.0, and can even become new opportunities in the life of the social, economic and educational fields. For this reason, it demands a policy of increasing hours of study for religious, moral and cultural education. The use of information technology in learning with blended learning; and learning in the network is a necessity that must be followed in integrating entrepreneurial values, both in formal and non-formal educational institutions.Contribution/Originality: It contributes to the analysis of the moderation of quality education, that professional teachers actually can integrate cultural and entrepreneurial values, eventually students possess attitudes, knowledge, skills, and actions in accordance with the demands of the industrial revolution 4.0.