The interaction on hypertension between family history and diabetes and other risk factors

Abstract

To explore the individual effect and interaction of diabetes and family history and other risk factors on hypertension in Han in Shanghai China. The method of case–control study with l:l matched pairs was used, 342 cases of hypertension and 342 controls were selected and investigate their exposed factors with face-to-face. The method of epidemiology research was used to explore the individual effect and interaction of diabetes and family history and other risk factors on hypertension. The individual effect of family history (OR = 4.103, 95%CI 2.660–6.330), diabetes (OR = 4.219, 95%CI 2.926–6.083), personal taste (OR = 1.256, 95%CI 1.091–1.593), drinking behavior (OR = 1.391, 95%CI 1.010–1.914) and smoking behavior (OR = 1.057, 95%CI 1.00–1.117) were significant (p < 0.05). But individual effect of sex, education, occupation, work/life pressure, environmental noise, sleeping time and sports habit were not significant (p > 0.05). The OR of interaction between FH and DM to hypertension was 16.537 (95%CI 10.070–21.157), between FH and drinking behavior was 4.0 (95%CI 2.461–6.502), FH and sport habit was 7.668 (95%CI 3.598–16.344), FH and personal taste was 6.521 (95%CI 3.858–11.024), FH and smoking behavior was 5.526 (95%CI 3.404–8.972), FH and work/life pressure was 4.087 (95%CI 2.144–7.788). The SI of FH and DM was 2.27, RERI was 8.68, AP was 52.48% and PAP was 55.86%. FH and DM, personal taste, smoking behavior had positive interaction on hypertension, but FH and sport habits, drinking behavior, work/life pressure had reverse interaction on hypertension. FH and diabetes were very important risk factors with significant effect for hypertension. FH and diabetes, personal taste, smoking behavior had positive interaction on hypertension, but FH and sport habits, drinking behavior, work/life pressure had reverse interaction on hypertension.

Effect of Hypertension, Waist-to-Height Ratio, and Their Transitions on the Risk of Type 2 Diabetes Mellitus: Analysis from the China Health and Retirement Longitudinal Study

“…Moreover, T2DM with hypertension has been regarded as an independent risk factor for severe organ involvement [ 8 ]. Growing evidence has demonstrated that hypertension and T2DM usually occurred successively [ 9 ], and compared with normotensive individuals, hypertensive individuals were 2.5 times more likely to develop T2DM within 5 years [ 10 ].…”

Cardiovascular (Framingham) and type II diabetes (Finnish Diabetes) risk scores: a qualitative study of local knowledge of diet, physical activity and body measurements in rural Rakai, Uganda

“…A total of 15 interviews were conducted with 9 women and 6 men. The median age was 44 years (range 35-49) for men and 37 (range [35][36][37][38][39][40][41][42][43][44][45] for women. Participants' occupations were substance agriculture/farming (4) (small scale farmers producing largely for their home use), trader/vendor/shopkeepers (5), fisherfolk (2), government/clerical workers (2), restaurant/waiter (1) and a housewife (1).…”

Association Between ABCA1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population

“…Family history of hypertension was a crucial marker of genetic factors, it was used as an alternative indicator to study the relationship between genetic factors and diseases frequently ( 36 ). The speedy economic growth, especially with a higher dietary salt intake, was another new and crucial factor related to the increased prevalence of hypertension in China, and quite a few lines of proof that include epidemiological observations, animal studies, and clinical trials have constantly proven a causal relationship between dietary salt consumption and hypertension ( 37 , 38 ). Excess dietary salt consumption was also an essential risk factor for the development and progression of cardiovascular disease.…”