“…General topics involved in these proposals include stability and/or controllability assessments (Yuan et al, 2011a,b), input-output pairing problems (Bristol, 1966;Chang and Yu, 1990;McAvoy et al, 2003;He et al, 2009;Assali and McAvoy, 2010), operating cost and self-optimizing (Skogestad, 2000;Alstad and Skogestad, 2007;Downs and Skogestad, 2011), performance and/or robustness indicators (Grosdidier et al, 1985;Skogetad and Morari, 1987;Skogestad and Postlethwaite, 2005), and deviation-based indexes or some combination of these into a multi-objective criteria (Downs and Skogestad, 2011;Sharifzadeh and Thornhill, 2012). Usually, the suggested design framework considers all possible degrees of freedom in a classical control structure (centralized/full or decentralized/diagonal).…”