In order to identify the epidemiological features of the incidence of COVID-19 in the Jalal-Abad region of the Kyrgyz Republic, a retrospective epidemiological analysis was carried out, according to the results of which the following was established. Jalal-Abad region was the leader in the number of cases of new coronavirus infection in the Kyrgyz Republic in 2020. The incidence had a pronounced rise with a maximum in October. The most disadvantaged in this period in terms of the incidence of a new coronavirus infection were Mailuu-SUU (1663.2 per 100 thousand), Chatkal (1000.8 per 100 thousand), Jalal-Abad (677.6 per 100 thousand) and Kara-Kol (532.0 per 100 thousand). In all territorial entities of the region, cases of COVID-19 were registered mainly among the adult population. The diseases of the new coronavirus infection in children were isolated. The greatest proportion of cases occurred in people aged 30–64 years, which is due to the larger number of this group, as well as the most severe course of the disease. Most often, the diseases occurred in the form of moderate severity (47.2 %) and mild (22.7 %). At the same time, according to the results of laboratory studies, it was possible to identify 14.9 % of cases of the disease with an asymptomatic course. The condition was regarded as severe in 12.2 % of cases, extremely severe — in 3 %. High focality was revealed. The share of foci with two cases was 63.2 %, with three — 19.3 %, four — 6.2 %, five — 5.5 %, six or more — 5.8 %. Most foci with four or more cases were registered in Ala-Buka, Suzak, Toktogul, Nooken districts and the city of Tash-Komur. The study made it possible to identify the features of the course of the epidemic process of a new coronavirus infection, which made it possible to adjust the implementation of preventive and anti-epidemic measures in the future, to reduce the rate of focality, to minimize mortality. At the same time, the main role in the prevention of COVID-19 from the moment of registration of vaccines against this infection is assigned to specific prevention.
