The role of fine‐needle aspiration cytology of the testis in the diagnostic evaluation of infertility

Abstract

Objective To compare the diagnostic value of cytological (all spermatogenic cells present except spermatids and spermatozoa). There was a good correlation between smears of fine-needle aspirate with that of histological sections obtained by testicular biopsy in the evaluation the diagnosis on the cytological smears and histological sections in 58 of 60 patients (97%). In two patients of infertility. Patients and methods The study included 60 patients there was scanty aspirate and few cells, giving an inaccurate diagnosis. Interstitial cells were not with azoospermia or severe oligospermia (sperm counts of < 5 million/mL). A detailed history was detected on cytological smears. In three patients, Sertoli-cell only was diagnosed on cytology, and histaken and the external genitalia examined. Testicular samples were obtained by fine-needle aspiration using tology revealed additional features of Leydig cell hyperplasia. a 10 mL syringe and 21 G needle; the air-dried smears were stained using the May-Grunwald-GiemsaConclusion Fine-needle aspiration of the testis is a simple and minimally invasive technique for diagnostic evalumethod. A testicular biopsy was taken after exploring the same tract and these sections were stained with ation, especially in patients with obstructive azoospermia. Patients with abnormal findings on fine-needle haematoxylin and eosin. The cytological smears and histological sections were examined separately and aspiration cytology may be evaluated histologically by further biopsy. the results compared. Results The cytological smears were divided into three

Role of Fine Needle Aspiration Cytology in Nonneoplastic Testicular and Scrotal Lesions and Male Infertility

“…[8][9][10][11] The cytologic findings in cases of infertility recapitulate the different histologic categories, and FNA has the potential to replace testicular biopsy in the assessment of spermatogenesis. Any discrepancy between cytology and histology is primarily the result of inadequate sampling rather than differences in the diagnosis.…”

Patterns of Testicular Cytology in Men with Primary Infertility

“…Fine needle aspiration (FNA) biopsy was introduced as a less invasive and safer diagnostic tool for diagnosing male factor. 4,5,8,9 The concordance rate of FNA and histologic diagnosis reached > 85% in many studies, with high specificity and sensitivity reaching > 95%. 5,[10][11][12][13][14] There has been growing concern among medical and nonmedical media in Jordan in the last decade about an increase in infertility rates due to male factor, presumably from various noxious insults after the 1991 Gulf War.…”

Touch Imprint Cytology in Biopsy of the Infertile Testis

“…Similar difficulties are described in the literature. 8,[10][11][12] Touch imprint preparations provide a rapid means of examining the cellular contents of the seminiferous tubules. Because mature, intact spermatozoa are clearly identified in this manner, such cytologic preparations are useful in distinguishing late maturation arrest from normal spermatogenesis; that distinction is sometimes difficult on frozen and paraffin sections.…”

“…4 The correlation between material from fine needle aspiration cytology and histology is reported in the range of 87-97.%. 3,11,12 Insufficient material affects the results. In our study, cytology correlated …”