The role of gastric muscle relaxation in cytoprotection induced by San-huang-xie-xin-tang in rats

San-Huang-Xie-Xin-Tang attenuates inflammatory responses in lipopolysaccharide-exposed rat lungs

“…San-Huang-Xie-Xin-Tang (SHXT), a traditional oriental medicinal formula containing Coptidis rhizoma (Coptis chinesis Franch), Scutellariae radix (Scutellaria baicalensis Georgi) and Rhei rhizoma (Rheum officinale Baill), has been used to treat gastritis, gastric bleeding and peptic ulcers (Lin and Tan, 1994). In our previous study, we have analyzed its components and, in spite of other unknown chemical components included in SHXT, baicalin is the most abundant one.…”

San-Huang-Xie-Xin-Tang reduces lipopolysaccharides-induced hypotension and inflammatory mediators

“…San-Huang-Xie-Xin-Tang (SHXT), a traditional oriental medicinal formula containing Coptidis rhizoma (Coptis chinesis Franch), Scutellariae radix (Scutellaria baicalensis Georgi) and Rhei rhizoma (Rheum officinale Baill), has been used to treat gastritis, gastric bleeding and peptic ulcers (Lin and Tan, 1994). Coptidis rhizoma yields 6.71-13.78% of alkaloids with 50-80% being berberine, and small amounts of coptisine, palmatine, worenine and epiberberine, etc.…”

Effects of San-Huang-Xie-Xin-Tang on U46619-induced increase in pulmonary arterial blood pressure

“…SHXT has been used to treat gastritis, gastric bleeding, peptic ulcers (Lin and Tan, 1994) and hypertension (Chen and Hsieh, 1986a,b;Sanae et al, 2001). Post-treatment with SHXT attenuated LPS-induced inflammatory responses (Lo et al, 2005a), lung edema and lethality (Lo et al, 2005b).…”