The Toxicity of Mauli Banana (Musa Acuminata) Stem Water Extract on Bone Marrow Mesenchymal Stem Cell in Vitro

Nindia, Amy; Aspriyanto, Didit; Apriasari, Maharani Laillyza; Rizky, Selviana

doi:10.22159/ijap.2019.v11s1.16762

Cited by 3 publications

(4 citation statements)

References 13 publications

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“…MB has a tannin content of 67%, and the tannins found in bananas are condensed tannins or proanthocyanidins. 13,16,26 Proanthocyanidins effectively strengthen the collagen fiber matrix, which is the organic matrix of dentin, and keep collagen fibers from degradation. 27 Proanthocyanidins can inhibit demineralization by reducing collagen degradation by dentine proteases, inhibiting proteolytic activity, and protecting dentin from enzymatic degradation.…”

Section: Discussionmentioning

confidence: 99%

“…One of the herbal ingredients that has been shown to affect caries and wound healing is the Mauli banana stem. 13,14 Mauli banana (MB) stem is a South Kalimantan native plant with numerous benefits, including anti-caries activity. The research of Apriasari et al 14 stated that MB extract has effective antibacterial activity against Streptococcus mutans.…”

Section: Introductionmentioning

confidence: 99%

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Demineralized dentin characteristics after application of Mauli banana stem gel

Carabelly,

Puspitasari,

Syahrina

et al. 2024

Dent. J.

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Background: Demineralization of dentin is a condition of dissolving minerals in peritubular dentin due to exposure to acids that release hydroxyapatite ions. To prevent dentin demineralization, a therapeutic agent that can inhibit the dissolution ability of hydroxyapatite ions is needed. One therapeutic agent that can be used is the Mauli banana (MB) stem gel. Purpose: To observe the characteristics of dentin demineralization after the use of MB stem extract gel. Method: Mandibular incisor bovine teeth were demineralized with lactic acid pH 4.5 for 72 hours and then treated with 25%; 37.5%; 50%; and 62.5% MB gel and Chlorhexidine 2% for one minute. All samples were soaked in artificial saliva with 1 mg/ml saliva of collagenase enzyme for 24 hours. The characteristic of dentin demineralization was observed by using scanning electron microscope/electron dispersive X-ray spectroscopy (SEM-EDX). Results: The SEM image in the control, Chlorhexidine, 25%; 37.5%; 50%; and 62.5% MB gel groups showed dentinal tubules of about 3.67–4.94 µm; 3.55–4 µm; 4.18–5.6 µm; 2.28–2.86 µm; 3.29–3.81 µm; and 2.42–3.17 µm in size. The EDX test found carbon (C), nitrogen (N), oxygen (O), sodium (Na), phosphorous (P), chlorine (Cl), and calcium (Ca) in all groups. The one-way Analysis of Variance (ANOVA) test results showed significant differences in the levels of C, N, O, Cl, and Ca between all groups, while the Na showed no significant differences. Conclusion: The MB can inhibit the demineralization of bovine dentin based on the decrease in the size of the dentinal tubules and increasing the C, O, P, and Ca.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Demineralized dentin characteristics after application of Mauli banana stem gel

Carabelly,

Puspitasari,

Syahrina

et al. 2024

Dent. J.

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“…19 The main ingredients contained in the banana mauli stem are tannins (67.69%), saponins, (14.49%), alkaloids (0 , 34%), and flavonoids (0.25%). 3 Previous studies conducted by Apriasari et al (2013) have proven that extracts of banana mauli stem at a concentration of 25% can inhibit the growth of Streptococcus mutans. 2 The results of Apriasari's research (2014) show that mauli banana extract at a concentration of 80% has the ability to inhibit the growth of Streptococcus mutans.…”

Section: Introductionmentioning

confidence: 99%

ANTIBACTERIAL ACTIVITY OF MIXED MAULI BANANA STEM AND BASIL LEAVES AGAINST Staphylococcus aureus

Budipramana¹,

Christanti²,

Apriasari³

et al. 2023

Dentino

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Background: Mauli banana is a typical plant in South Kalimantan which contains tannins (67.59%), saponins (14.49%), alkaloids (0.34%), and flavonoids (0.25%) as natural antiseptics inhibiting the growth of Streptococcus mutans. Basil is plant that contain eugenol (70%), flavonoids (4.75%), tannins (4.6%), and alkaloids (1%) as natural antiseptics inhibiting the growth of Candida albicans. This study was to examine the antibacterial activity of a mixture of banana mauli stem stems and basil leaves against Staphylococcus aureus. Purpose: to analyze the antibacterial activity against Staphylococcus aureus in the mixture of banana mauli stems and basil leaves extracts. Method: true experiment using pretest and posttest with control group design with 11 treatments consisting of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 100%, and aquadest. Antibacterial activity test was conducted using dilution method. Determination of Minimum Inhibitory Concentration (MIC) was determined by contrasting the absorbance value before and after incubation. Minimum Bactericidal Concentration (MBC) was obtained by testing the concentration with negative absorbance value on MSA media incubated for 24 hours. Results: The results of this study indicated that the concentration of 40%, 50%, 60%, 70%, 80%, 90%, and 100% could inhibit the growth of Staphylococcus aureus but these concentrations had yet been able to kill Staphylococcus aureus. Conclusion: The MIC of mauli banana and basil leaves extract combination against S aureus presentts at 40% concentration yet MBC cannot be obtained.Keywords : Antibacterial activity, Basil leaf, Dilution method, Mauli banana stem, Staphylococcus aureus

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“…Inflammatory conditions of the pulp that can be treated by pulpcapping are pulpal diagnosis in the form of reversible pulpitis. 8 Pulpcapping treatment is divided into indirect pulpcapping and direct pulpcapping. Indirect pulpcapping is a treatment to maintain the pulp to keep it vital by placing the pulp protection agent on the base of the cavity where the pulp chamber is still covered with a layer of dentin.…”

Section: Introductionmentioning

confidence: 99%

Propolis Extract Sorption as a Pulpcapping Agent

Erlita¹,

Rahmatillah²,

Diana³

2021

Dentino

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Background: This research is an experimental study to determine the physical properties of propolis extract as an alternative material in pulpcapping treatment. High sorption value is the main cause of pulpcapping treatment failure. Purpose: to analyze the sorption value of propolis extract in water and artificial saliva. Materials and Methods: Thirty disc-shaped zinc oxide propolis (15 mm x 1 mm) specimens were stored in the incubator at 37ºC for 24 hours. The discs were weighed, dehydrated, and weighed again. Immediately after weighing, the discs were immersed for 1 day, 3 days, and 7 days in 50 mL of distilled water and artificial saliva at 37ºC and then weighed for second time (sorption value). Data were analyzed by one way ANOVA for data processing in the water and artificial saliva immersion group, then the Independent T-Test for inter-group immersion in water with artificial saliva. Results: There were differences in the sorption value of zinc oxide propolis with ZnOE (positive control) in water and artificial saliva between immersion times of 1 day, 3 days, and 7 days. There was no difference in the sorption value of zinc oxide propolis between the water and the artificial saliva immersion group. Conclusion: The sorption value of propolis extract, both in water and artificial saliva immersion shows a high sorption value. This indicates that the propolis extract has not met the criteria as a pulpcapping material in terms of its physical properties, namely absorption of water (water sorption).Keywords: Propolis extract, Pulpcapping, Sorption

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The Toxicity of Mauli Banana (Musa Acuminata) Stem Water Extract on Bone Marrow Mesenchymal Stem Cell in Vitro

Cited by 3 publications

References 13 publications

Demineralized dentin characteristics after application of Mauli banana stem gel

Demineralized dentin characteristics after application of Mauli banana stem gel

ANTIBACTERIAL ACTIVITY OF MIXED MAULI BANANA STEM AND BASIL LEAVES AGAINST Staphylococcus aureus

Propolis Extract Sorption as a Pulpcapping Agent

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