The utility of intraoperative ECoG in tumor-related epilepsy: Systematic review

Zhu, Qiang; Liang, Yuan; Fan, Ziwen; Liu, Yukun; Zhou, Chunyao; Zhou, Hong; Li, Tianshi; Zhou, Yanpeng; Yang, Jun; Wang, Lei

doi:10.1016/j.clineuro.2021.107054

Cited by 13 publications

(18 citation statements)

References 41 publications

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“…Most studies suggest routine use of ECoG for those with a long history of uncontrolled seizures. 24,33,34 However, Englot believes the use of intraoperative ECoG during low-grade glioma and glioneuronal tumor resections was not associated with statistically different seizure outcomes, according to systematic studies of these procedures. 19,35 The role of ECoG in epilepsy-related tumor surgery still requires con rmation through large-scale randomized control studies to develop the best surgical approaches.…”

Section: Discussionmentioning

confidence: 99%

Tumor-Related Epilepsy and Post-Surgical Outcomes: Tertiary Hospital Experience in Vietnam

Nguyen

Pham

et al. 2023

Preprint

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Purpose: Seizures have a significant impact on the quality of life of those who suffer. This study aimed to evaluate the variables that influence the incidence of seizures during the perioperative period and effective measures to enhance epilepsy outcomes among individuals undergoing surgical resection of brain tumors. Methods: The authors carried out a prospective observational analysis of all patients who experienced seizures before their brain tumor surgery at UMC, HCMC between 2020 and 2022. Results: 54 cases presented with seizures were enrolled for the study, generalized seizure was the most prevalent seizure type (61.1%), followed by focal seizure (29.6%). Low-grade gliomas and frontotemporal lobe tumors increase the postoperative risk of seizure. Other predictive factors are a prolonged history of seizure, especially resistant epilepsy and major peritumoral edema. In contrast, gross total resection reduces postoperative seizure incidence. There was correlation between Ki67 proliferation index and seizure incidence in both low-grade and high-grade gliomas. ECoG made insubstantial difference in enhancing the epilepsy surgery outcome. Overall, 88.9% of patients were seizure-free at 6 months of follow-up (Engel Class I), 7.4% were almost seizure-free (Class II), and 3.7% had significant improvement (Class III), figures for 12-month follow-up were 87.0%, 9.3%, and 3.7% respectively. Conclusion: The majority of patients presented with seizures are those who were diagnosed with glioma. Postoperatively, most of the patients were seizure-free or had meaningful improvement. A shorter history of seizure and gross-total resection appear to be associated with a favorable prognosis for seizure control.

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Section: Discussionmentioning

confidence: 99%

Tumor-Related Epilepsy and Post-Surgical Outcomes: Tertiary Hospital Experience in Vietnam

Nguyen

Pham

et al. 2023

Preprint

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“…However, to the best of our knowledge, no study has synthesized the literature on this topic. 23 We conducted a systematic review and individual patient data (IPD) meta-analysis (IPDMA) to investigate the clinical efficacy and utility of iECoG in epilepsy surgery. This study will provide epilepsy teams with the clinical evidence for routine implementation of iECoG into operative practice for appropriately selected patients.…”

Section: Key Pointsmentioning

confidence: 99%

“…Given the heterogeneity of iECoG use in resective epilepsy surgery, it is important to assess the utility of the current "gold standard" interictal‐based iECoG. However, to the best of our knowledge, no study has synthesized the literature on this topic 23 . We conducted a systematic review and individual patient data (IPD) meta‐analysis (IPDMA) to investigate the clinical efficacy and utility of iECoG in epilepsy surgery.…”

Section: Introductionmentioning

confidence: 99%

Clinical utility of intraoperative electrocorticography for epilepsy surgery: A systematic review and meta‐analysis

et al. 2022

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Despite the widespread use of intraoperative electrocorticography (iECoG) during resective epilepsy surgery, there are conflicting data on its overall efficacy and inability to predict benefit per pathology. Given the heterogeneity of iECoG use in resective epilepsy surgery, it is important to assess the utility of interictalbased iECoG. This individual patient data (IPD) meta-analysis seeks to identify the benefit of iECoG during resective epilepsy surgery in achieving seizure freedom for various pathologies. Embase, Scopus, and PubMed were searched from inception to January 31, 2021 using the following terms: "ecog", "electrocorticography", and "epilepsy". Articles were included if they reported seizure

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“…Epileptic activity often arises in patients with gliomas ( Ghinda et al., 2021 ; Saito et al., 2018 ), thus some patients with brain tumors undergo intraoperative ECoG monitoring, typically during awake craniotomy ( Goldstein and Feyissa, 2018 ; Yao et al., 2018 ). The presence of high-frequency oscillations in the ECoG signal seems to be a spatial marker of the epileptogenic zones in brain tumor-related epilepsy ( Feyissa et al., 2018 ; Peng et al., 2021 ; Quitadamo et al., 2018 ; Sun et al., 2022 ; van Klink et al., 2021 ; Zhang et al., 2021 ), even though there is some disagreement between researchers ( Robertson et al., 2019 ; Zhu et al., 2022 ). Apart from epileptogenic zone identification, intracranial recordings are also used to functionally map cortical regions before or during surgery.…”

Section: Cortical Bmis Beyond Motor Controlmentioning

confidence: 99%