Therapeutic effect of the NMDA antagonist MK-801 on low-level laser induced retinal injury

Yan, Wanchun; Wu, Jianhuang; Chen, P.; Dou, Jingtao; Pan, Chang Yu; Mu, Yiti; Lu, Jie

doi:10.1134/s1054660x09030232

Cited by 6 publications

(4 citation statements)

References 40 publications

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“…Also red blood cells [35] and retina [36,37] have been investigated as PDT targets. Most often hematoporphyrin derivatives, such as Photofrin R , Photogem R and Photosan R , and chlorin-e6-derivatives, such as Photodithazine R [35], are used as photosensitizers.…”

Section: Introductionmentioning

confidence: 99%

“…In most lasers based photodynamic therapy (PDT) studies colon cancer cells were used as a target [23][24][25][26][27][28][29][30][31][32][33][34]. Also red blood cells [35] and retina [36,37] have been investigated as PDT targets. Most often hematoporphyrin derivatives, such as Photofrin R , Photogem R and Photosan R , and chlorin-e6-derivatives, such as Photodithazine R [35], are used as photosensitizers.…”

Section: Introductionmentioning

confidence: 99%

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Optical image analysis of fat cells for indocyanine green mediated near-infrared laser treatment

et al. 2011

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Fat tissue engineering by near-infrared laser treatment is investigated in vitro. For the quantitative estimation of efficiency of treatment and consequential processes on the cellular level, a computational method for optical image analysis is proposed. The method is based on the fractal dimension data analysis of fat cell structure. The conducted experiments confirm the feasibility of the proposed method to obtain quantitative information of the cellular processes. The results indicate that the proposed method is promising for estimating spatial changes of biological structure. CCD cameraThermostatic Experimental setup consists of a CCD camera, thermostatic table, sample holder, and CW diode laser

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optical image analysis of fat cells for indocyanine green mediated near-infrared laser treatment

et al. 2011

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“…During the past few years, several therapeutic approaches have been tried to treat the laser-induced retinal degeneration. Retina transplantation, administration of N-methyl-D-aspartate (NMDA) receptor antagonist, or antioxidants or anti-inflammatory agents [12][13][14] have been tested. However, most of them require complicated procedures and some have significant local or systemic adverse effects.…”

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confidence: 99%

Protective effect of basic fibroblast growth factor on retinal injury induced by argon laser photocoagulation

Zhang²,

San

et al. 2010

Laser Phys. Lett.

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Laser photocoagulation treatment is often complicated by a side effect of visual impairment, which is caused by the unavoidable laser-induced retinal destruction. At present no specific is found to cure this retinopathy. The aim of this study was to observe the neuroprotective effect of bFGF on laserinduced retinal injury. Chinchilla rabbits were divided into three groups and argon laser lesions were created in the retinas. Then bFGF or dexamethasone, a widely used ophthalmic preparation, or saline was given severally by retrobulbar injection. The retinal lesions were evaluated histologically and morphometrically, and visual function was examined by ERG. The results showed that bFGF administration better preserved morphology of retinal photoreceptors and significantly diminished the area of the lesions. Furthermore, bFGF promoted the restoration of the ERG b-wave amplitude. In rabbits treated with dexamethasone, however, the lesions showed almost no ameliorative changes. This is the first study to investigate the potential role of bFGF as a remedial agent in laser photocoagulation treatment. These findings suggest that bFGF has significant neuroprotective properties in the retina and this type of neuroprotection may be of clinical significance in reducing iatrogenic laser-induced retinal injuries in humans. Time after exposure, day

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“…Laser is a phototherapy resource widely used for dentistry and medical proposes as tissue repair (bones, tendons, nerves, and muscles), destruction of malignant tissues as tumors (photodynamic therapy -PDT), inactivation of microorganisms (photodynamic antimicrobial chemotherapy -PACT), and survey of physical-chemical data from a sample (spectroscopy) [4][5][6][7][8][9][10][11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Dentin hypersensitivity clinical study comparing LILT and LEDT keeping the same irradiation parameters

et al. 2010

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Dentin hypersensitivity is a common condition associated with high dental pain. A new LED-based (light emitting diode) light source has been used as an experimental tool in some studies. Purpose: The main objective was to compare these two light sources emitting in the same spectral band (redfrom 625 to 660 nm) to promote pain relief. Material and methods: A total of 6 sessions were accomplished, being three irradiation sessions and three follow-up sessions. This single-blind study compared a control group (Placebo) and two other groups with different equipments: low laser intensity treatment (LILT) and a light emitting diode system treatment (LEDT). Results: The results showed that there is no statistical difference between LILT and LEDT groups, however, both were better than control group (p ≤ 0.01) in terms of treatment efficiency; there is no difference between the second and the third sessions for both treatment, it means that the third session was not necessary; finally, the improvement at the end of the entire research (follow up care of 30 days) was very expressive in comparison to pre-treatment situation for all teeth (p ≤ 0.01). Conclusion: LILT and LEDT were equally effective to treat dentine hypersensitivity, a 3rd treatment session was not necessary/two sessions are enough.Irradiation spots (3 at the cervical area and 1 at the apex)

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Therapeutic effect of the NMDA antagonist MK-801 on low-level laser induced retinal injury

Cited by 6 publications

References 40 publications

Optical image analysis of fat cells for indocyanine green mediated near-infrared laser treatment

Optical image analysis of fat cells for indocyanine green mediated near-infrared laser treatment

Protective effect of basic fibroblast growth factor on retinal injury induced by argon laser photocoagulation

Dentin hypersensitivity clinical study comparing LILT and LEDT keeping the same irradiation parameters

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