Hazardous waste landfill is the final way to dispose of hazardous waste and its environmental risk is different from that of domestic waste landfill. Its dangerous characteristics will not decrease with time, but will exist for a long. The environmental risks of hazardous waste landfills are concentrated in the probability risk of leakage of the impermeable layer. Therefore, it is of great significance to calculate the environmental risk of the leakage source intensity of typical hazardous waste landfills. In order to adapt to the personalized customer needs caused by social and economic development and to pursue new competitive advantages, the production mode of manufacturing enterprises is gradually changing to a small-batch and multi-variety customized mode. The complex and dynamic production environment caused by determinism puts forward higher requirements for the operation control accuracy of large-scale multiunit production systems. To support the efficient and coordinated operation of each link is a key challenge for process control of large-scale multiunit production logistics systems. This article proposes to accelerate the integration of information technology and manufacturing technology to promote the application of intelligent manufacturing process, intelligent logistics management, and other technologies in the production process. The research object is to study the multiunit linkage optimization problem under the framework of digital twin technology, through the real-time collaborative decision-making and feedback execution of the production, transportation, and warehousing multi-decision links to solve the “production-transportation-storage” decision-making in a dynamic environment. We analyzed the problems brought about by the dynamic interference of the execution process on the “production-transportation-storage” linkage operation process of the industrial park and analyzed the challenges of realizing the online linkage decision-making of “production-transportation-storage.” Based on the classic digital twin framework, a cross-unit digital twin linkage decision information architecture is proposed. Compared with the conclusions of the original environmental impact assessment report of the project, the post-environmental impact assessment results basically conform to the relevant descriptions, and a few nonconformities have been resolved during the project operation. The environmental protection measures of this project are relatively complete, which can meet various environmental protection requirements and enterprise development needs during the operation period of the project. For some environmental risks found in the process of project operation, evasion measures are proposed to reduce the possibility of environmental pollution accidents, and emergency measures can be taken in time when accidents occur. The practice of post-assessment of the environmental impact of this hazardous waste landfill is generally successful, and it has certain reference significance for the subsequent post-assessment of the environmental impact of other hazardous waste landfills.