Toxicity and Environmental Risk of Oxytetracycline and Effect in Leukocytes of Mato Grosso (Hyphessobrycon eques)

Fujimoto, Rodrigo Yudi; Gabbay, M. I.; Anjos, E. C.S.; Carraschi, Silvia Patrícia; Cruz, Claudinei da

doi:10.5132/jbse.2012.02.002

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…Neotropical fish sensitivity is similar to B. rerio, with higher sensibility to potassium chloride than Pimephales promelas (7.62 g L -1 LC 50 ;96 h) (USEPA, 2001). The fish sensibilities were similar as described for H. eques (1.5 g L -1 ) (Fujimoto et al, 2012) and for P. mesopotamicus (1.33 g L -1 ) (Carraschi et al, 2012).…”

Section: Fish Sensitivitysupporting

confidence: 74%

Sensitivity, ecotoxicity and histopathological effects on neotropical fish exposed to glyphosate alone and associated to surfactant

Cruz¹,

Shiogiri²,

Silva³

et al. 2016

J. Environ. Chem. Ecotoxicol.

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The aim of this research was to evaluate neotropical fish sensitivity (Piaractus mesopotamicus, Phallocerus caudimaculatus, Hyphessobrycon eques, and Brachydanio rerio) to a reference substance (potassium chloride); to estimate the lethal concentration (LC 50 ; 96 h) for glyphosate, formulated as Rodeo ® alone and in association with 0.5 and 1.0% Aterbane ® BR surfactant and to evaluate the histopathology of the gills, liver, and kidney from the fish after acute exposure. P. caudimaculatus and H. eques are good bioindicators like B. rerio because they have similar sensitivity. The LC 50 ;96 h for glyphosate alone and in association with 0.5% Aterbane ® BR was similar (>975.0 mg L-1) for all the fish. Aterbane ® BR alone was the most toxic substance to P. caudimaculatus (5.81 mg L-1 LC 50 ;96 h) and glyphosate associated to 1.0% Aterbane ® BR was more toxic to H. eques (411.91 mg L-1 LC 50 ;96 h). The glyphosate alone and in association with Aterbane ® BR was classified as practically non-toxic, whereas Aterbane ® BR alone was considered moderately toxic for the tested organisms. The histopathological effects caused by glyphosate exposure on gills, liver, and kidneys are reversible, except for the liver necrosis on P. caudimaculatus. H. eques, P. caudimaculatus, and P. mesopotamicus present great potential to be used as standard organisms for herbicides monitoring and the use of glyphosate without surfactant addition is enough to cause histological alterations on H. eques and P. caudimaculatus, which makes them possible to be applied on environmental monitoring studies as biomarkers.

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Section: Fish Sensitivitysupporting

confidence: 74%

Sensitivity, ecotoxicity and histopathological effects on neotropical fish exposed to glyphosate alone and associated to surfactant

Cruz¹,

Shiogiri²,

Silva³

et al. 2016

J. Environ. Chem. Ecotoxicol.

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“…Pode-se inferir, neste estudo, que a sua redução está associada com o estresse ocasionado pelo óleo diesel, tendo em vista que o estresse prolongado pode provocar imunossupressão, debilitando o sistema imunológico dos organismos submetidos a xenobióticos (FUJIMOTO et al, 2012). Similaridade foi percebida por ALI et al (2014), que observaram redução no número de linfócitos do tecido sanguíneo de Fundulus grandis expostos ao petróleo.…”

Section: Tabelaunclassified

Alterações leucocitárias ocasionadas pelo estresse toxicológico agudo do óleo diesel em juvenis de tilápia-do-nilo

et al. 2018

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ABSTRACT:This study aimed to evaluate the stress and changes in white blood cell count of juveniles Oreochromis niloticus subjected to acute toxicity of diesel oil. The toxicity was evaluated in a completely randomized design with five dilutions (20, 25, 30, 35 and 40%) and one control, both with three replicates. For the assessment of blood glucose levels and changes in white blood cell count, blood was drawn by caudal puncture of the dying fish. It was concluded that diesel oil can present risks to aquatic ecosystem, causing toxicity and physiological changes to fish. KEYWORDS: physiological changes; fish; derived oil; leukogram. RESUMO:O presente trabalho teve como objetivo avaliar o estresse e as alterações no leucograma dos juvenis de Oreochromis niloticus submetidos à toxicidade aguda do óleo diesel. A toxicidade foi avaliada em um delineamento inteiramente casualizado com cinco diluições (20, 25, 30, 35 e 40%) e um controle, ambos com três repetições. Para a avaliação dos níveis glicêmicos e alteração no leucograma, foi retirado sangue por punção caudal dos peixes moribundos. Dessa forma, conclui-se que o óleo diesel pode apresentar riscos ao ecossistema aquático, provocando toxicidade aos organismos aquáticos e alterações fisiológicas. Alterações leucocitárias ocasionadas pelo estresse toxicológico agudo do óleo diesel em juvenis de tilápia-do-nilo PALAVRAS-CHAVE:

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“…The impacts of the use of antibiotics on aquatic organisms can be assessed through ecotoxicological studies on several species, determining the effects or lethality of various substances (Fujimoto et al 2012). Conversely, sh are exposed to stressful conditions during management in sh farms, and stress is a response to any situation that alters their normal metabolism causing changes in the physiological state and biochemical alterations (Hoseini et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Acute toxicity, risk assessment and exposure of Nile tilapia larvae after stress to sub-lethal concentrations of oxytetracycline

Takeshita

Chiste

Jonsson

et al. 2022

Preprint

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Median lethal concentration (LC50 − 96h), risk assessment, development, and mortality of Nile tilapia Oreochromis niloticus larvae exposed to oxytetracycline (OTC) after stress management were evaluated in this study. Fish (n = 126; 32.25 ± 3.74 mg; 13.01 ± 0.64 mm; 7 larvae/aquarium) were used for LC50 − 96h trial and randomly distributed in 21 aquaria (1 L) with 0.0, 2.01, 2.44, 3.31, 3.65 and 4.59 mg/L of OTC. For acute stress test, fish (n = 180; 33.9 ± 0.73 mg; 13.06 ± 0.72 mm; 10 larvae/aquarium) were submitted to air stress for 5 minutes and posteriorly randomly allocated in 18 aquaria (1 L) and exposed to 0.0, 0.03, 0.82, 1.65, 2.47 and 3.30 of OTC. Temperature, pH, dissolved oxygen (DO), conductivity, total ammonia and total hardness were measured daily. LC50 − 96h of OTC for Nile tilapia larvae was 3.45 mg/L. Weight and length of larvae submitted to graded levels of OTC decrease in both tests. Significant differences was observed for DO over 96h. pH, temperature and DO differ (P < 0.05) in post-stress test. Stress management (exposure to air) potentiates the toxic effects of sub-lethal doses of OTC. Furthermore, based on the risk quotient, OTC has a high risk to Nile tilapia larvae when exposed to therapeutic concentrations.

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Toxicity and Environmental Risk of Oxytetracycline and Effect in Leukocytes of Mato Grosso (Hyphessobrycon eques)

Cited by 4 publications

References 8 publications

Sensitivity, ecotoxicity and histopathological effects on neotropical fish exposed to glyphosate alone and associated to surfactant

Sensitivity, ecotoxicity and histopathological effects on neotropical fish exposed to glyphosate alone and associated to surfactant

Alterações leucocitárias ocasionadas pelo estresse toxicológico agudo do óleo diesel em juvenis de tilápia-do-nilo

Acute toxicity, risk assessment and exposure of Nile tilapia larvae after stress to sub-lethal concentrations of oxytetracycline

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