Triterpenoids fromDrypetes chevalieriBeille (euphorbiaceae)‡‡

Abstract

The CH2Cl2/CH3OH (1/1) extract of the dried stem of Drypetes chevalieri Beille afforded two new triterpenoïds named drypechevalin A (11-oxo-beta-amyrin-3beta-ylcaffeate) and drypechevalin B (3,7-dioxo-D:A-friedooleanan-24-al) along with five known compounds: lupeol, lupeone, erythrodiol, putranjivadione, friedelin. Their structures were established on the basis of spectroscopic analysis and chemical evidence.

Steroids and Ceramide from the Stem Bark of Odyendyea gabonensis

“…Its 1 H NMR spectrum (Table 1) , and 2.20 ppm (brs, H-12b) due to protons adjacent to the carbonyl groups and one additional methyl group at δ = 2.19 ppm (s) confirming the presence of an acetate function. In addition, it showed a signal at δ = 4.37 ppm (brs) attributed to H-3, confirming the location of the acetate group at C-3 position, in agreement with the reported data [15]. The positions of the two carbonyl functions were determined by HMBC and EI-MS spectra.…”

“…482.3396). The presence of the carbonyl and enone functions was revealed by strong absorptions at 1735 and 1655 cm −1 in the IR spectrum and confirmed by a strong absorption at 245 nm in the UV spectrum [15]. Its 1 H NMR spectrum (Table 1) , and 2.20 ppm (brs, H-12b) due to protons adjacent to the carbonyl groups and one additional methyl group at δ = 2.19 ppm (s) confirming the presence of an acetate function.…”

Antimicrobial and antioxidant effects of phenolic constituents fromKlainedoxa gabonensis

“…A total of 40 fractions of approximately 100 mL each were collected and combined on the basis of similar TLC. Fractions 1-10 were further chromatographed over silica gel 60 with a mixture of n-hexane-CH 2 Cl 2 (1:1) to yield β-amyrin (7) (15.5 mg) and erythrodiol (8) (20.5 mg) (Wansi et al, 2006). Fraction C was chromatographed over a silica gel 60 column with a CH 2 Cl 2 , CH 2 Cl 2 -EtOAc gradient.…”

“…A total of 35 fractions of approximately 100 mL each were collected and combined on the basis of similar TLC. Fractions 1-25 were further chromatographed on silica gel 60 with a mixture of n-hexane-CH 2 Cl 2 (8:2) to yield fatty acids (25 mg) (Andersen & Gorbert, 2002), a mixture of sterols (β-sitosterol and stigmasterol) (30.4 mg) (Morris et al, 1984), and lupeol (5) (19.3 mg) (Wansi et al, 2006). Fraction B was chromatographed over a silica gel 60 column with an n-hexane-CH 2 Cl 2 gradient.…”

Análise de terpenóides de espécies de Croton sect. Lamprocroton (Mull. Arg.) Pax (Euphorbiaceae)

“…Triterpenos e esteróides são compostos bastante comuns em Euphorbiaceae (Martinez-Vasquez et al, 1999;Wansi et al, 2006;Rubalcava et al, 2007) 18-4,4,6a,6b,8a,11,11,14b-Octametil-1,4,5,6,6a,6b,7,8, 9,10,11,12,14,14a, 19 -ácido ursenóico 28 -ergost-5-en-3-ol (Agarwal et al, 2003;Mendes et al, 2004;Magalhães et al, 2008) anti-leischmania (Cardoso-Lopes et al, 2009) e anti-artrite (Magalhães et al, 2008). Em Croton são descritos para um grande número de espécies, como C. zambesicus (Mohamed et al, 2009), C. tiglium (Mendes et al, 2004), C. betulaster (Barbosa et al, 2003), C. eluteria (Fattorusso et al, 2002) e C. pulley (Abreu et al, 2001).…”