Über die Bedeutung der Adenylsäure für die Muskelfunktion. I. Mitteilung: Das Vorkommen von Adenylsäure in der Skelettmuskulatur.

Embden, Gustav; Zimmermann, Margarete

doi:10.1515/bchm2.1927.167.1-3.137

Cited by 65 publications

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“…In the late 1920s, Embden's group (58,59) discovered muscle adenylic acid, but its significance was not immediately obvious (123, p. 14). In 1928, Karl Lohmann (1898-1978) found a substance in trichloroacetic acid extracts of muscle that could be hydrolyzed into inorganic phosphate (107,108).…”

Section: The Phosphagen Buffer Systemmentioning

confidence: 99%

The Metabolic Systems: Anaerobic Metabolism (Glycolytic and Phosphagen)

Brooks

Gladden

2003

Exercise Physiology

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I N this chapter, we address the history of the study of anaerobic metabolism during exercise. Our emphasis is on the early origins and progression of studies on phosphagen and glycolytic metabolism. Further, although our topic is "anaerobic" metabolism, we consider the interrelationship between oxygen and lactic acid production to be of primary importance. Other areas of this broad topic receive less attention; space limitations required us to focus on what we believe to be the more important events and their consequences. For information on studies and scientists before approximately 1900, we relied heavily on Fletcher and Hopkins (63), Keilin (99), Leicester (105), von Muralt (153), Rothschuh (141), Williams (164), and Zuntz (168).THE PRELACTIC AciD ERA Fennentation and the Pasteur EffectDespite the fact that von Muralt (153) called the study of muscle metabolism before 1907 the "prelactic acid era," numerous important observations relating to glycolysis and lactic acid were made during this period. The notion that lactic acid is formed as the result of oxygen lack can be traced to alcohol fermentation technology of the 322 C. M. Tipton (ed.), Exercise Physiology

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Section: The Phosphagen Buffer Systemmentioning

confidence: 99%

The Metabolic Systems: Anaerobic Metabolism (Glycolytic and Phosphagen)

Brooks

Gladden

2003

Exercise Physiology

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“…In 1927, Gustav Embden and Margarete Zimmermann described adenosine monophosphate in skeletal muscle (Embden & Zimmermann 1927). Adenosine 5′‐triphosphate (ATP) was discovered in 1929 independently by Karl Lohmann in Germany and by Cyrus Hartwell Fiske and Yellagaprada SubbaRow in the USA (Fiske & SubbaRow 1929, Lohmann 1929).…”

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confidence: 99%

The birth and postnatal development of purinergic signalling

et al. 2010

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The purinergic signalling system is one of the most ancient and arguably the most widespread intercellular signalling system in living tissues. In this review we present a detailed account of the early developments and current status of purinergic signalling. We summarize the current knowledge on purinoceptors, their distribution and role in signal transduction in various tissues in physiological and pathophysiological conditions.

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Nucleinsäuren

Bredereck

1934

Angewandte Chemie

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290 Bredereck: Fortschritte d. physiol. Chem. seit 1929. I. Naturstaffe. NucleinsZIuren welcher Weise der enzymatisch aktive Anteil in ihnen verkniipft vorliegt, ob als integrierender Bestandteil des Eiweifimolekiils selbst oder mit diesem nur in mehr oder Komponenten zuzuordnen haben. [A. 54.1 Wirkungen der einzelnen Enzyme wird man jedenfalls ganz spezifischen, noch nicht gekennzeichneten aktiven weniger fester Form assoziiert, also abtrennbar, erscheint indessen noch nicht sicher entschiedensl). Die spezifischen U. G . Tewes, ebenda 215, 93 [1933]. E. Waldschmidt-Leilz u. 9 Lsvene u. Tipson, Journ. biol. Chemistry 97, 491 [1932].

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Über die Bedeutung der Adenylsäure für die Muskelfunktion. I. Mitteilung: Das Vorkommen von Adenylsäure in der Skelettmuskulatur.

Cited by 65 publications

References 0 publications

The Metabolic Systems: Anaerobic Metabolism (Glycolytic and Phosphagen)

The Metabolic Systems: Anaerobic Metabolism (Glycolytic and Phosphagen)

The birth and postnatal development of purinergic signalling

Nucleinsäuren

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