Urinary Excretion of Neutral 17-ketosteroids and Pregnanediol by Patients with Prostatic Cancer and Benign Prostatic Hypertrophy

Urinary Hormone Metabolite Levels in Patients With Cancer of the Breast, Prostate and Lung*

“…Ratios of androsterone: etiocholanolone in both the cancer and emphysema groups were significantly lower than in the well control group.7 Patients with lung cancers of the adenocarcinoma, squamous and anaplastic types had significantly lower androster0ne:pregnanediol ratios than did clinically well subjects. 7 The well controls. In addition to a lowered androsterone: etiocholanolone ratio, a drop also is noted in the ratio of 11-desoxy-17-ketosteroids: 1 1-oxy-17-ketosteroids.…”

Four Primary Malignant Tumors, Including Malignant Melanoma and Malignant Lymphoma, in the Same Adult Patient

“…It is thus possible that BCG and radiation could have also affected the immune surveillance system of the patient. Marmorston et al (17) suggest that hormonal imbalances associated with aging tend to increase the incidence of prostatic cancer in males. Furthermore, aging in general makes people susceptible to tumors.…”

Prostate cancer and the multiple primary malignant neoplasm syndrome

“…Hormones are felt to be associated with an increased risk of multiple tumors [52-551. While prostate cancer is a male malignancy, estrogens may play a role in its etiology inasmuch as some investigators have suggested that prostate cancer is the result of a disproportional increase of the estrogedandrogen ratio resulting from a relative decline in androgen production [56].…”