Use of Medicines from the Group of Benzodiazepines in the Period of 2003-2013 Year in the Republic of Macedonia

Petrushevska, Tatjana; Stefanovska, Vesna Velik

doi:10.3889/oamjms.2015.004

Cited by 6 publications

(1 citation statement)

References 27 publications

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“…In the Republic of Macedonia, between 2003 and 2013, of all the patients requiring treatment with benzodiazepine, 59% were treated with 5 mg diazepam [14]. In Bosnia, diazepam was the most common psychotropic agent for outpatient uses between 2002 and 2008, followed by phenobarbital and carbamazepine [15] [17].…”

Section: Efforts To Ensure Diazepam Availability For Medical Usesmentioning

confidence: 99%

Ten-Year Retrospective Study of Diazepam Consumption in Indonesia

Priyatni

Hasanbasri

Mustofa

et al. 2017

Asian J Pharm Clin Res

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Objective: This study aimed to evaluate annual consumption during 2004-2013 of diazepam, an essential medicine which is controlled under the 1971 Convention on Psychotropic Substances in Indonesia and to investigate factors influencing its use in health facilities. Methods:This was a case study with quantitative and qualitative approaches. Annual consumption was calculated from the quantity of exports and imports. The use of diazepam was calculated from consumption deducted by 20% buffer stock. The consumption and use of diazepam were presented in kilogram and also in defined daily doses for statistical purposes (S-DDD). In-depth interviews were conducted to investigate factors that influence the use of diazepam. Triangulation was conducted to confirm the qualitative and quantitative findings. Considering the approximate need of diazepam to treat various health problems, its use should ideally be around 1-2 S-DDD. Therefore, the calculated use of diazepam was considered too low as confirmed by frequent stockouts. The interviews revealed that among the factors influencing its use was its limited production. There was an increased use of alprazolam, but it was unlikely to compensate for the diazepam stockouts. Conclusion:Consumption and use of diazepam for medical purposes in Indonesian decreased over 10 years, and stockouts are often reported. The government should improve its availability and correct impediments for adequate production and supply of diazepam.

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Section: Efforts To Ensure Diazepam Availability For Medical Usesmentioning

confidence: 99%