Water-soluble complex formation of fullerenes with a biocompatible polymer

Preparation and photo-induced activities of water-soluble amyloid β-C60 complexes

“…The absorption of anthracene moiety of ADPA is reduced by the oxidation of ADPA with ROS species, and can be used to quantify ROS. 15 The Φ ROS value of Aβ40-C 60 was estimated from the magnitude of the decrease in the absorption of ADPA with photoexcitation of Aβ40-C 60 ( Fig. 7 ).…”

“…Chemical modications such as the addition of hydroxyl groups have been performed to solubilize fullerenes in water. [9][10][11][12][13] Other methods such as the inclusion of organic macromolecules, [14][15][16] laser ablation, 7,17 and solvent substitution methods 18 have also been proposed. A variety of water-soluble fullerene derivatives have now been chemically synthesized; however, a sufficient amount of fullerene derivative seems not to be readily prepared in many cases.…”

Preparation of a thermo-responsive drug carrier consisting of a biocompatible triblock copolymer and fullerene

“…[32][33][34] We have reported that a water-soluble complex (C 70 /PMPC) can be synthesized by mixing C 70 and PMPC powders and grinding them. 35 0.49 g L À1 C 70 can be solubilized in water using 1 g L À1 PMPC.…”

Polysaccharide-fullerene supramolecular hybrids: Synthesis, characterization and antioxidant activity

“…Next to covalent fullerene chemistry [5], the noncovalent functionalization of fullerene C 60 with water-soluble carriers that can form host-guest complexes represents a fast-developing strategy for the preparation of C 60 -based hybrid nanomaterials. Supramolecular incorporation of C 60 in special carriers like cyclodextrins [7][8][9][10][11][12], calixerenes [13], biocompatible polymers, such as polyvinylpyrrolidone [14,15], poly (2-(methacryloyloxy)ethyl phosphorylcholine [16], PEG [17], and poly(2oxazoline)s [18,19], as well as liposomes [20,21], proteins [22], and antibiotic doxorubicin [23], gives soluble complexes without changing the physical properties of the fullerene sphere. In addition, increasingly complex molecular systems for solubilization and studies of fullerene were used.…”