Wheezing, asthma, hayfever, and atopic eczema in childhood following exposure to tobacco smoke in fetal life

Magnusson, Linda L; Olesen, Anne Braae; Wennborg, Helena; Olsen, Jørn

doi:10.1111/j.1365-2222.2005.02374.x

Cited by 122 publications

(93 citation statements)

References 63 publications

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“…A preponderance of evidence from multiple large prospective studies indicates that prenatal exposure to ETS is associated with impaired respiratory function, transient wheeze, asthma, and/or respiratory infections in infants, young children, and adolescents (24,25). It is evident that prenatal exposure to ETS alters airway structure, because greater distances between alveolar attachments in intraparenchymal airways have been measured among exposed infants who died of sudden infant death compared with unexposed infants (26).…”

Section: Prenatal Environmental Exposures Gene Interactions and Astmentioning

confidence: 99%

Environmental Epigenetics and Asthma

Miller¹,

Ho²

2008

Am J Respir Crit Care Med

258

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Section: Prenatal Environmental Exposures Gene Interactions and Astmentioning

confidence: 99%

Environmental Epigenetics and Asthma

Miller¹,

Ho²

2008

Am J Respir Crit Care Med

258

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“…A review also found that effective tobacco smoke control can rapidly reduce the prevalence of respiratory diseases [21]. However, several studies found no association between parental smoking and asthma [22,23], wheeze [23,24], hay fever [24,25] or rhinitis [3,25]. Moreover, a study conducted by ISAAC Phase One Study Group, found that "countries that have high adult male smoking rates have a lower risk of asthma and rhinitis symptoms in children" [26].…”

mentioning

confidence: 99%

Associations between indoor environmental smoke and respiratory symptoms among preschool children in Shanghai, China

Liu

Huang

et al. 2013

Chin. Sci. Bull.

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Whether indoor environmental smoke is harmful for preschool children's respiratory health in a society where female smoking is rare has not been determined. This study is part of a cross-sectional study (CCHH study-phase one in Shanghai) and investigated associations between parental smoking and incense-burning and respiratory symptoms among 4-6 year old children in Shanghai, China. A number of 13335 valid questionnaires (response rate: 85.3%) were analyzed. A number of 56.1% (as reported by a parent) of preschool children in Shanghai are exposed to environmental tobacco smoke (ETS). A number of 40.3% of fathers and 0.9% of mothers are smokers. A number of 53.7% and 12.6% of Shanghai residents have used mosquito-repellent incense and incensation respectively. Children exposed to any parental smoking have higher prevalence of wheeze and croup than those not exposed. Current maternal smoking has a significant and positive association with wheeze (in the last 12 months, AOR, 95% CI: 1.83, 1.11-2.99). However, paternal smoking either currently or at child's birth had only weak associations with wheeze and croup. Incense-burning (mosquito-repellent incense and incensation) had significant and negative association with doctor-diagnosed asthma (AOR, 95% CI: 0.85, 0.73-0.99) and hay fever (AOR, 95% CI: 0.80, 0.70-0.93). The results indicate that maternal smoking perhaps is a stronger risk factor for children's respiratory health than paternal smoking. environmental tobacco smoke, incense, asthma, wheeze, preschool children, Shanghai

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“…In both mice and humans, development of T1D requires the interaction of a genetically susceptible host and an environmental insult. Investigation of the genetic basis of T1D susceptibility in NOD mice and com parison of the results with genome scans in humans with T1D have confirmed that many of the same processes are involved in this disease in both species (2). Although more than 20 loci have been described, the major genes that govern T1D susceptibility in both mice and humans map in the major histocompatibility complex.…”

Section: Public Health Implicationsmentioning

confidence: 99%