Wide field snapshot imaging polarimeter using modified Savart plates

Saito, Naooki; Odate, Satoru; Kubota, Masahiro; Kitahara, Rintaro; Oka, Koichi

doi:10.1117/12.2022829

Cited by 8 publications

(3 citation statements)

References 4 publications

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“…Many examples of this approach with ideal input Stokes vectors can be found in the literature. 45,46,50,51 Here, we focus on a United States Air Force 1951 (USAF) target. Some of the artifacts associated with the methodology, such as errors in reconstruction in the presence of edges, can be noted in Fig.…”

Section: Fourier Reconstructionmentioning

confidence: 99%

Design and implementation of a portable colposcope Mueller matrix polarimeter

et al. 2020

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Section: Fourier Reconstructionmentioning

confidence: 99%

Design and implementation of a portable colposcope Mueller matrix polarimeter

et al. 2020

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“…The polarization microscope is a custom instrument developed by Nikon (Oka and Saito (2006); Saito et al (2013)), which consists of an episcopic illumination system capable of dark-field illumination in five wavelengths and a polarimetric imaging system for measuring the state of polarization of scattered light from the tissue sample positioned at the microscope’s specimen stage (Figure 1B,C). A Nikon bright-field objective lens with minimal polarization distortion (Nikon XFI TU Plan Fluor EPI) was used to operate within the epi-illumination and dark-field imaging constraints of this polarimeter.…”

Section: Methodsmentioning

confidence: 99%

Backscattering Mueller Matrix polarimetry on whole brain specimens shows promise for minimally invasive mapping of microstructural orientation features

Bonaventura

Morara

Carlson

et al. 2022

Preprint

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Understanding microscale physiology and microstructural cellular features of the brain is key to understanding the mechanisms of neurodegenerative diseases and injury, as well as the prominent changes that neurons and glia in the brain undergo in development and aging which reflect functional state. Non-invasive imaging modalities sensitive to the microscale - especially diffusion magnetic resonance imaging (dMRI) - are extremely promising for three-dimensional mapping of cellular microstructure of brain tissues and brain connectivity via tractography; however, there is a need for robust validation techniques to verify and improve the biological accuracy of fiber orientation information derived from these techniques. Recent advances in dMRI acquisition and modeling have moved toward probing of the more complex grey matter architecture, challenging current validation techniques, which are largely based on ex vivo staining and microscopy and focused on white matter. Polarized light imaging (PLI) has been shown to be a successful technique for high resolution, direct, microstructural imaging and has been applied to dMRI validation with clear advantages over conventional staining and microscopy techniques. Conventionally, PLI is applied to thin, sectioned samples in transmission mode, but unlike histologic staining, PLI can be extended to operate with high sensitivity in reflectance mode and even extended to 3D imaging to bridge the gap toward in vivo validation of dMRI measurements of orientation features in both gray and white matter of the brain. In this report we investigate the use of backscattering Mueller Matrix polarimetry to characterize the microstructural content of intact Ferret brain specimens. The experimental results show that backscattering polarimetry can probe white matter fiber coherence and fiber orientation in whole brain specimens, and show promise for probing grey matter microstructure. Ultimately, these preliminary results motivate further study to fully understand how backscattering polarimetry can best be used for validation of in vivo microstructural imaging of the brain.

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“…Unfortunately, the Savart plates must be designed depending of the need of the system, of a specific thickness, furthermore these polarimeters work at narrow optical bandwidth [50] although some investigators have been able to push this limit up to 50 nm [51].…”

Section: (B))mentioning

confidence: 99%

A review of polarization-based imaging technologies for clinical and preclinical applications

Ramella‐Roman

Saytashev

Piccini

2020

J. Opt.

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Polarization-based imaging can provide new diagnostic capabilities in clinical and preclinical studies. Various methodologies of increasing complexity have been proposed by different groups in the last 30 years. In this review we focus on the most widely used methods in polarization imaging including co- and cross-polarized-based imaging, Mueller matrix imaging, and polarization sensitive optical coherence tomography, among others. This short primer in optical instrumentation for polarization-based imagery is aimed at readers interested in including polarization in their imaging processes.

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Wide field snapshot imaging polarimeter using modified Savart plates

Cited by 8 publications

References 4 publications

Design and implementation of a portable colposcope Mueller matrix polarimeter

Design and implementation of a portable colposcope Mueller matrix polarimeter

Backscattering Mueller Matrix polarimetry on whole brain specimens shows promise for minimally invasive mapping of microstructural orientation features

A review of polarization-based imaging technologies for clinical and preclinical applications

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