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generation rate decreased in the presence of the studied compounds, evidencing for their antiradical activity.Increase of superoxide dismutation activity of the biopreparation in the presence of compounds 1-10 was also shown, and this fact could indicate their ability to increase the antioxidant status and decrease the probability of oxidative stress development. It was found that compounds 1-10 did not inhibit enzyme lipoxygenase, which indicated the absence of antiinflammatory activity. The results of the forecast were consistent with the data of the experimental studies.

By using PASS online web resource, it was predicted that phosphorus-containing derivatives of 2,6-di-tert-butylphenol had high probability to possess antioxidant activity and to act as active oxygen metabolite "traps" and heavy metal antidotes. The values of the acute toxicity index of phosphorus-containing phenols for rats, aquatic organisms, and bioaccumulation factor, calculated by the GUSAR programme, indicate potentially low toxicity. The results of the forecast are comparable with the data of experimental studies in vitro and in vivo experiments.

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