Helminth infections are among the most widespread infections in humans. Ficus benghalensis L. (Moraceae) is traditionally used in Indian system of medicine. Anthelmintic activity was evaluated using worms as experimental models. Test sample of Ficus benghalensis aerial roots extracts was prepared at the concentration 10, 25, 50mg/ml in normal saline solution. Standard drug used Albendazole (20mg/ml). Time for death of worms were recorded after ascertaining that worms neither moved when shaken vigorously nor when dipped in warm water (50o c). Phytochemical constituents such as Phenolics, tannins, saponins, mucilage and alkaloids may be responsible for the anthelmintic activity. It may be concluded that methanolic extract of Ficus benghalensis possesses significant anthelmintic property.
Moringa oleifera is a medium-sized tree that stands 10-12 metres tall. It is also known as the “Drumstick” tree, the horseradish tree, and the mother’s closest friend. The leaves of Moringa oleifera have an abundance of minerals like calcium, potassium, zinc, magnesium, iron, and copper. When pathogens enter the body via food, the condition is often called "food poisoning." Hydro-alcoholic extraction, simple distillation was subjected to powdered Moringa oleifera leaf. The extract was again heated using a water bath, and the crude drug was obtained. In vitro, anti-bacterial screening is performed by the disc diffusion method. Escherichia coli-Gram-negative bacteria were grown on nutrient agar in the refrigerator. Similarly, streptomycin was prepared as a standard antibacterial drug. The test drug and standard drug of streptomycin were compared for their zone of inhibition. Parameters such as organoleptic, microscopic, physical and chemical were evaluated. The presence of an alkaloid confirms the antibacterial activity. The 500 mg of orally disintegrating tablet was prepared by the direct compression method using a 10 mm diameter stainless steel die. Along with the crude drug powder, microcrystalline cellulose (MCC) was used as a diluent/binder and mannitol as a sweetener. The tablet was further evaluated.
All over Saudi Arabia, the medicinal plant Calotropis procera (C. procera) is a common wild shrub. We looked into the phytochemical makeup and several extracts of C. procera in this work. The presence of different ingredients was checked in all extracts. Table displays the findings of this exploratory phytochemical investigation. Following a phytochemical analysis, it was discovered that Calotropis procera contains alkaloids, steroids, flavonoids, tannins, and terpenoids. To separate the active compounds that might have pharmacologically active ingredients, a TLC chromatographic research was conducted. Ethanol and chloroform extract of Calotropis procera leaves demonstrate the presence of flavonoids and phenolic substances in preliminary phytochemical testing. Additionally, the TLC of both extracts reveals the presence of several phytometabolites. After collection of all fractions of both ethanol and chloroform extract, these fractions then screened for anti-rheumatic arthritis activity. Results depict that 150 mg/kg of crude extract and ethanolic fraction on 10th day showed more superior repression of paw edema i.e., 80.26% and 81.25% (p < 0.001) as compared to 79.56% reduction in paw edema by 100 mg/kg aspirin on 10th day.
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