Elias ACGP, Matsuo T, Cardoso LTQ, Grion CMC. Aplicação do sistema de pontuação de intervenções terapêuticas (TISS 28)

This study evaluated the use of the POSSUM (Physiological and Operative Severity Score for Enumeration of Mortality and Morbidity) score for predicting mortality in surgical practice. In this study, 416 surgical patients admitted into ICUs for post-surgical care were analyzed. Both predicted and actual mortality rates were compared, according to four risk groups: 0-4%, 5-14%, 15-49%, 50% and over, and the area under the ROC curve of the POSSUM and APACHE II for mortality. The POSSUM and APACHE II scores overestimated the risk of death. The area under the ROC curve of the POSSUM was 0.762, and under APACHE II was 0.737, suggesting the use of POSSUM as an auxiliary tool to predict the risk of death in surgical patients.

ResumoA pesquisa relata os resultados de um protocolo para prevenção de úlcera de pressão (UP) em pacientes críticos na unidade de terapia intensiva -1 do Hospital Universitário Regional do Norte do Paraná. O protocolo foi elaborado pelos enfermeiros do setor seguindo as orientações da AHCPR. Foram admitidos 51 pacientes sem UP durante o período de 1 mês, sendo avaliados diariamente por um enfermeiro, até a sua alta da unidade. Dos 51 pacientes, 29 (57%) foram considerados com risco de desenvolver UP. Destes, 12 apresentaram algum estágio de UP, sendo que 7 (58%) apresentaram alterações em duas áreas corporais e 5 (47%) em uma área corporal. As duas áreas corporais mais atingidas foram sacro e tornozelo (72%) e cotovelo e maléolo lateral (14%). A alteração em uma área corporal ocorreu em 40% no cotovelo, 20% maléolo lateral e 40% no tornozelo. Os 12 pacientes de risco que desenvolveram algum estágio de UP tiveram valores de hemoglobina abaixo de 10 g/dl e receberam transfusão de hemoderivados. O estudo demonstrou que o trabalho com o protocolo traz resultados efetivos para encontrar o paciente de risco, estabelece cuidados preventivos e otimiza recursos adequados na solução do problema UP. Palavras-chave: úlcera de pressão; protocolo; Escala de Braden, prevenção AbstractThis study reports the outcomes of a protocol for the prevention of pressure ulcer at an intensive care unit. The protocol was elaborated by nurses that working together in a teaching hospital. The nurses followed the recommendations proposed by AHCPR for the prevention of pressure ulcer. During one month, 51 patients free of pressure ulcers at admission were assessed through this protocol. Twentynine (57%) patients from this group risk developing pressure ulcers, but only 12 developed some stages of pressure ulcer. From this group of 12 patients, 7 (58%) developed pressure ulcer in two areas of the

The sesquiterpenoid fractions from the chloroform extracts of roots and aerial parts of the weed Cyrtocymura cincta (Griseb.) H. Robinson (Compositae) were tested to observe the effects on seed germination and growth of three dicot and four monocot species. Promotion and inhibition effects were observed according to the examined compound, specific seed or cultivar, and concentration.

Phytochemicals (PHT) are a large group of biologically active plant chemicals that may have positive effects on human health such as immune system stimulation, down regulation of inflammatory responses, radical scavenging activities, cell repair function, and antibacterial and antiviral activity. In this proof of principle 6 months study, the effects of supplementing a PHT mix, Phyto V7, to HIV-1 seropositive individuals and AIDS patients were examined. Individuals with CD4+ T-cells below 350 counts/mm 3 were assigned to one of the following treatments: CG1 -no treatment, CG2 -only highly active antiretroviral treatment (HAART), TG1 -only Phyto V7, and TG2-both Phyto V7 and HAART. After 3 months of treatment there were approximately (-)1%, 1%, 2% and 4% increase in the mean weight of the CG1, CG2, TG1 and TG2 groups, respectively. The tendency for the body mass index (BMI) was similar. The CD4+ counts increased by 13%, 39%, 53% and 35%, respectively. Similar trends were noted after 6 months with 2%, 79%, 53% and 69% increases in the CD4+ counts, respectively. There was a significant reduction in viremia only in groups receiving HAART. Overall better results were obtained in the group of patients receiving both HAART and Phyto V7, in which the mean weight increased by 5.7% and the CD4+ T-cell counts increased by 69% after 6 months. This study indicates that providing Phyto V7 to HIV-1 seropositive individuals and AIDS patients, receiving or not receiving HAART, improves their physical wellbeing and CD4+ counts, enabling them to cope better with the viral infection.