The bioassay directed phytochemical investigations of Tribulus longipetalus have resulted the isolation of eighteen compounds and their structures havebeen elucidated by extensive use of modern spectroscopic (UV, IR, EIMS, HREIMS, 1 H NMR, 13 C NMR, FAB +ve, FAB -ve) techniques. All the compounds have been isolated for the first time from this species.

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Ayurveda with safe and effective goodness has been pouring its valuable treasures to mankind since time unknown. Guggulu preparations are supposed to be one among the finest shaman aushadha in the Vata vyadhis. Literature enlists a number of such guggulu preparations in the management of Vatarakta. In the present study literature regarding Gokshuradi Guggulu quoted in Sharangadhar Samhita for the management of Vatarakta is expounded with all possible details. Individual drugs of the chosen formulation is expanded with respect to their synonyms, botanical details including Latin name, family, botanical description and parts used, Rasa Panchaka, chemical constituents and modern research references related to Gout that can prove beneficial for mankind.

India stands 27th in rank with 25.8% of death rate due to Liver diseases in 2016. In spite of scientific advancement in the field of Hepatology, Bio-medical science is clueless in finding out an effective drug against Hepatic Disorders. Detailed description on liver disorders and their management are given by all the three prominent Acharyas of Ayurveda. Rasa Bhasma is one such preparation that can be used to treat Hepatic Disorders. In present work an attempt has been made to evaluate the efficacy of Rasa Bhasma in the management of liver disorders. 24 animals were allocated into 4 groups having six animals in each group namely Group I (Normal/Control), Group II (Intoxicated Control) Toxicated Group, Group III (lower dose of Rasa Bhasma) and Group IV (Higher dose of Rasa Bhasma). All the four group were assessed for various biochemical Parameters viz. Alkaline phosphatase, SGOT (Serum glutamate oxalacetate transaminase)/AST, SGPT (Serum glutamate pyruvate transaminase)/ALT, Total Bilirubin, Direct Bilirubin and Total Proteins. Finally, the animals from all the four groups were sacrificed for Histo-pathological studies. The results were expressed as mean ± SE and One way ANOVA by using statistical software SPSS version 16.0. Results revealed that the values of Group 4 are closer to the Normal Group1 than Group 3 meaning Rasa Bhasma in Higher dose is more effective than that in lower dose. Therefore, it can be concluded that Rasa Bhasma is a potent Herbo-mineral formulation for protection of hepatic cells.