BACKGROUND: The mental health of medical students has long been a topic of concern in many countries. Much research in Europe reported that around 30% of medical students suffered from anxiety. Anxiety disorders have significant physical and emotional consequences. Various studies show that excessive, unmanaged stress related to poor academic performance in medical students leads to cynical personalities, lack of empathy, and suicidal ideas. AIM: This study aimed to identify studies for psychotherapy interventions carried out in medical students and analyze each impact on anxiety level in medical students. METHODS: This systematic review was conducted with evidence sourced from 2000 to 2020. The review process followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The study was registered with the Prospective Registering of Systematic Reviews database (Protocol ID: CRD42020180650). RESULTS: Twenty-three studies meet the inclusion criteria, and there are various psychotherapy interventions to deal with anxiety. Most studies reported that students who received mindfulness-based interventions reported lower anxiety, depression, and stress. CONCLUSION: There are various interventions carried out to decrease stress levels, depression, and anxiety in medical students. The most effective psychotherapy was found in cognitive and behavior intervention and mindfulness intervention.

Background: Self-harming behavior (SHB) is an iceberg phenomenon commonly occurred in both normal population and patients with mental illness. This behavior showed an increase in trend and may develop into suicidal behavior if not treated properly. Therefore an effort in screening and prevention of self-harm is necessary to prevent early deaths caused by suicide. Currently Indonesian version of self-harm screening instrument has not been developed yet.Purpose: Conducting validity and reliability test of Indonesian version of self-harm questionnaire.Method: This research was a descriptive analytic study with cross-sectional design. We recruited 110 psychiatric outpatients from Bantul Hospital Yogyakarta (n=110). SHB was measured using Indonesian version of Self Harm Inventory (SHI). Internal validation was tested using Aiken's Validity Index (AVI) and Pearson Product Moment Correlation (PPMC). Reliability was tested using Cronbach Alpha (CA). Statistical significance was defined as p<0,05.Result: The respondents consisted of 57 men (51.8%) and 53 women (48.2%). Twenty four respondents had done more than 5 items of SHB. AVI value ranged from 0.83 to 0.97 which considered good. PPMC obtained 21 valid items with correlation coefficient >0.25 (p <0.05). Item number 22 was excluded because coefficient value was <0.25. Rresult of Keizer Meyers Oklin was 0,686 and Barlett Test of Spherecity 0,000 (p <0,05). CA was 0.831 which means very good.Conclusion: Indonesian version of Self-Harm Inventory is a valid and reliable screening tool against self-harm behavior in clinical setting.

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Abstract   Introduction Schizophrenia is a neuropsychiatric disease that is global and is experienced by 1% of the population in the United States and Europe. This study raises awareness of the role of infectious agents in the initiation of psychotic symptoms in schizophrenia. Case Presentation A 20-year-old man is taken by the family to the emergency department because he has decreased consciousness, and the body suddenly stiffens. Patients begin to experience changes in behavior in the form of difficulty sleeping, when invited to talk quietly, laughing alone and whispering without the other person. TORCH examination found an increase in anti-toxoplasma IgM and IgG. This patient is then given basic life support in the form of ABC (airway, breathing, circulation support) and seizure management. Also given risperidone 2 mg / 12 hours, pyrimethamine 1-II (1x200 mg), pyrimethamine day III-XXI (1x 25 mg), intravenous Cefotaxim 2g / 8 hours, Clindamycin 500 mg / 8 hours. The patient experienced improvement after the second week of treatment. Conclusion Toxoplasmosis causes lesions in the brain that cause changes in brain neurotransmitter pathways, which lead to changes in patient behavior.