Coronavirus disease 2019 (Covid-19) is a disease caused by the corona virus which can cause respiratory tract infections with up to severe symptoms. SARS-CoV-2 virus infection can cause symptoms ranging from symptoms (asymptomatic), mild, moderate and severe symptoms. Until now, no antiviral or vaccine has been found that can infect Covid-19. Therefore, efforts to break the chain of transmission are the application of health protocols that include 3M recording, wearing masks and maintaining distance. However, there are still many community members, especially employees who are not yet obedient to implementing this protocol. Community service is carried out as an effort to prevent the transmission of Covid-19 to office employees in Bandar Lampung, considering that the work area is one of the areas that contributes to the high incidence of Covid-19 in Bandar Lampung. The community service activity was attended by 97 well-known employees in 13 offices in the Bandar Lampung area. The method used is health education through the zoom application. The questionnaire was given to measure participants before and after participating in activities. The material is presented using powerpoint audiovisual media and leaflets which are presented using the zoom application. This activity results showed an increase in participants' knowledge about covid-19 and covid-19 health protocols in the work area. Presenting information about covid-19 and covid-19 health protocols has a positive impact on increasing public knowledge, especially employees in office areas.

Cancer is a disease that is characterized by the existence of damage and cell abnormality in growth and differentiation. Liver cancer is a disorder of hepar tissue derivated from its tumors. Taurine is known as antioxidant but its role as anticancer needs to be explored more as well the role of Annona muricata leaf extract which is believed to have its role as anticancer substance. This research, therefore, aimed to explore the effect of taurine and Annona muricata leaf extract on the hepar histopathology of male mice (Mus musculus) induced by benzo(α)pyren in vivo. This research was carried out by using a complete randomized design, which consisted of 5 treatment groups which was repeated 5 times. Group I was given 0.2 mL corn oil for 15 days, group II was induced by benzo(α)pyren without taurin nor A. Muricata leaf extract for 10 days, group III was given 7.8 mg taurine/BW/day (twice a day) starting from the 15 th days before the induction of benzo(α)pyren, group IV, after induced with benzo(α)pyren, taurine was given with dosage of 7.8 mg/BW/day, group V, after induced with benzo(α)pyren, soursop leaf extract was given with amount of 277.8 mg/BW/day. Data analyzed by Kruskal-Wallis test and one way ANOVA with Fisher test (p>0.05). The results indicated that taurine had ability to recover the liver tissue induced by benzo(α)pyren as (carcinogenic) while, Annona muricata leaf extract had not shown any recover of tissue damage. ABSTRAKKanker merupakan suatu penyakit yang ditandai dengan adanya kerusakan dan ketidaknormalan sel dalam mengatur pertumbuhan dan diferensiasinya. Kanker hati adalah gangguan pada hepar yang berawal dari tumor hepar. Taurin diketahui sebagai senyawa antioksidan, namun perannya dalam antikanker perlu dieksplorasi lebih jauh, demikian pula dengan ekstrak daun sirsak yang telah diminati oleh masyarakat sebagai bahan antikanker. Penelitian ini bertujuan untuk mengetahui peran senyawa taurin dan ekstrak daun sirsak terhadap gambaran histopatologi hepar mencit (Mus musculus) yang diinduksi benzo(α)piren secara in vivo. Penelitian ini dilaksanakan dengan menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 5 kelompok perlakuan dengan masing-masing memiliki 5 ulangan, Kelompok I diberi 0,2 mL minyak jagung selama 15 hari, kelompok II diinduksi dengan benzo(α)piren tanpa pemberian bahan uji selama 10 hari, kelompok III pemberian taurin 7,8 mg/BB/hari (2 kali/hari) sejak 15 hari sebelum induksi benzo(α)piren), kelompok IV diinduksi benzo(α)piren dan dilanjutkan dengan pemberian taurin dosis 7,8 mg/BB/hari (2 kali/hari), kelompok V diinduksi benzo(α)piren, dilanjutkan pemberian daun sirsak dosis 277,8 mg/BB/hari. Data dianalisis dengan metode statistik menggunakan uji ANOVA satu arah

ABSTRAKAsam urat atau dalam bahasa medis dikenal sebagai hiperurisemia merupakan suatu penyakit yang kasusnya sering terjadi pada seseorang yang sudah lanjut usia. Asam urat menjadi salah satu penyakit yang bisa disebabkan karna proses penuaan selain juga karena adanya gangguan sirkulasi darah, gangguan pada persendian dan berbagai penyakit neoplasma lainnya. Hampir 8% orang yang berusia 50 tahun ke atas memiliki masalah asam urat dengan keluhan berupa nyeri sendi, pegal linu, dan nyeri yang dapat mengganggu aktivitas. Penanganan asam urat dapat dilakukan melalui terapi farmakologi / obat – obatan dan terapi non farmakologi. Akan tetapi, penanganan secara farmakologi pada lansia dalam jangka waktu yang cukup lama juga dapat berdampak terhadap masalah kesehatan lainnya terutama berkaitan dengan masalah ginjal. Penderita asam urat perlu memiliki pemahaman yang baik terkait masalah asam urat yang diderita, bagaimana upaya pengendaliannya, cara mendeteksi asam urat serta pengaturan gaya hidup terutama diit yang tepat bagi penderita asam urat. Tujuan dari pengabdian masyarakat ini adalah agar lansia mengetahui tentang asam urat mulai dari pengertian hingga pengendalian asam urat serta dapat memahami cara mendeteksi dini asam urat melalui gejala – gejala yang dialami. Kata kunci : asam urat; deteksi dini; pengendalian asam urat ABSTRACTGout or in medical language known as hyperuricemia is a disease that often occurs in elderly people. Gout is one of the diseases that can be caused due to the aging process as well as due to blood circulation disorders, disorders of the joints and various other neoplasms. Nearly 8% of people aged 50 years and over have gout problems with complaints of joint pain, aches and pains, that can interfere with activities. Treatment of gout can be done through pharmacological therapy / drugs and non-pharmacological therapy. However, pharmacological treatment in the elderly for a long period of time can also have an impact on other health problems, especially those related to kidney problems. Patients with gout need to have a good understanding of the gout problem they suffer, how to control it, how to detect gout and lifestyle settings, especially the right diet for gout sufferers. The purpose of this community service is so that the elderly know about gout from understanding to controlling gout and can understand how to detect gout early through the symptoms experienced. Keywords: gout; early detection; control of gout

Hipertensi atau penyakit darah tinggi adalah suatu keadaan dimana seseorang mengalami peningkatan tekanan darah di atas normal. Angka kejadian hipertensi di dunia mencapai sekitar 970 juta penderita, 330 juta terdapat di negara maju dan  640 terdapat di negara berkembang. Data pra survei menunjukkan angka kejadian hipertensi di Lampung Timur tahun 2017 mencapai 2.972 kasus dan di Puskesmas Tambah Subur mencapai 375 kasus. Salah satu upaya untuk menurunkan tekanan darah penderita hipertensi diantaranya dengan mengkonsumsi buah yang tinggi kalium seperti buah pisang ambon.  Desain penelitian ini menggunakan pre-experimental design, populasi dalam penelitian ini sebanyak 374 orang penderita hipertensi. Sampel yang digunakan sebanyak 25 orang dengan teknik pengambilan sampel menggunakan purposive sampling. Analisis dalam penelitian ini menggunakan uji paired t-test. Hasil uji statistik menunjukkan bahwa rata-rata tekanan darah penderita hipertensi sebelum (pre-test) pemberian buah pisang ambon adalah 149,00/94,52 mmHg dengan standar deviasi 5,132/2,468 dan setelah (post-test) pemberian buah pisang ambon 140,04/89,88 mmHg dengan standar deviasi 5,697/5,199. Hasil analisis dengan paired sample t-test didapatkan p-value 0,000 <  0,05 maka dapat disimpulkan bahwa ada pengaruh buah pisang ambon terhadap penurunan tekanan darah penderita hipertensi, dimana rata-rata tekanan darah penderita hipertensisetelah diberi perlakuan lebih rendah secara bermakna dibandingkan sebelum diberi perlakuan. Disarankan bagi penderita hiperhenti hendaknya dapat mempertahankan asupan diit tinggi buah terutama yang banyak mengandung tinggi air dan kalium.

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