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Corynebacterium renale is the etiological agent of a specific cystitis and pyelonephritis of cattle. Aberrant C. renale infections have been reported in a horse by Foss (1944), in horses and sheep by Boyd and Bishop (1937), and in a dog by Olafson (1930). Ernst (1906) and Jones and Little (1926) were unable to infect mice with C. renale. Lovell (1946) reported that C. renale was pathogenic for mice provided an adequate number were given intravenously. Morse and Morgan (1951) were able to infect mice by intravenous and intraperitoneal inoculations of strains of C. renale which were isolated from the urine or posterior urogenital tracts of apparently normal cattle. Morse and Wipf (1951) studied the epizootiology, pathogenicity, and pathogenesis of a diphtheroid which, although it resembled

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report there were some which needed adjustment of pH to the optimal value (7.2) with sodium bicarbonate after being added into the basal medium. These were L-glutamic acid, DL-aspartic acid, L-arginine hydrochloride, DL-lysine dihydrochloride, L-histidine hydrochloride and DL-ornithine hydrochloride. To correct the errors the experiments have been done using sodium hydroxide as a neutralizing substance in place of sodium bicarbonate. The results are shown in table 3. In each case the rate of the germination in the media containing caramel from glucose is higher than that reported in the previous report except in the case of L-glutamic acid. Hence conclusions mentioned in the previous report have partially to be corrected. DL-Aspartic acid, L-arginine and DL-ornithine may belong to the group which has a stimulative effect on both the growth and the germination.