H(2)S level may be negatively correlated with the process of inflammation and positively correlated with expression of CSE in nasal mucosa. The endogenous H(2)S pathway is down-regulated in AR.

Background: The mechanisms responsible for the development of allergic rhinitis(AR) are not fully understood. The present study was designed to explore the possible roles of carbon monoxide(CO) on the pathogenesis of AR.

Background: The involvement of CD4+CD25+ regulatory T cells (CD4+CD25+ TRegs) in allergic diseases was reported previously. However, it remains unclear whether CD4+CD25+ TRegs are involved in allergic rhinitis (AR). Methods: Fresh whole blood from 20 patients with AR and 16 healthy donors was used to investigate the frequency of CD4+CD25+ and CD4+CD25hi Treg cells using flow cytometry. In addition, serum total IgE (IU/mL) levels were determined using enzyme-linked immunosorbent assays. Results: Patients with AR had fewer CD4+CD25+ Treg cells (2.80 ± 1.36% vs. 3.94 ± 0.97%, P < 0.01) and CD4+CD25hi TRegs (1.53 ± 0·62% vs. 2.00 ± 0.52%, P < 0.05) than control subjects. The number of CD4+CD25+ and CD4+CD25hi TRegs was correlated negatively with total immunoglobulin E levels (r = –0.79, P < 0.01 and r = –0.61, P < 0.01, respectively). Conclusion: Deficient regulatory T cells might play a role in the development of AR.

Silicon solid-state small satellite (or nano satellite) is a new kind of aerospace aircraft, which adopt ideas greatly different from the conventional method. The small satellite is composed of ASIMs, which make the conventional complex system into a single system with IC and micro electronic mechanical system (MEMS) technologies. The fundamental principle of how to improve silicon-solid state small satellite in China is discussed here, as well as its application in special data store and forward communication. We also introduce our research of MEMS and its application in space. A practical design of data communication nano satellite about 15KG in weight and IO inch in line length is also given out.

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