Diabetes Mellitus is a disease characterized by hyperglycemia resulting from defects in insulin secretion. Garcinia Cambogia is an Asian plant used commonly as nutritional supplement for weight loss.Objective: The purpose of this study is to perform a mini review about Garcinia Cambogia consumption and its relationship with DM condition in humans.Methods: Studies were searched in Pubmed, Web of Science and Scopus databases and 62 articles were identified and reviewed in an integrative method. After a criterial analysis, 3 articles were included on this mini review.Results: Two studies found that Garcinia Cambogia in association with Glucomannan had a positive association related to comorbidities as Diabetes Mellitus and its markers (glycemia, triglycerides, cholesterol). However, a case report showed an adverse effect on a high dose Garcinia Cambogia consumption. Conclusion:It is possible that Garcinia Cambogia consumption influences Diabetes Mellitus condition, although more studies are necessary for higher efficacy understanding.

Olive oil has phenolic compounds, such as hydroxytyrosol, tyrosol e oleuropein. Through this rich composition, olive oil conditions its biological actions to neuroprotection, such reactive oxygen species, antioxidant and anti-inflammatory action, inhibition of lipid peroxidation, restoration of glutathione and anti-apoptotic properties.Objective: Conduct an integrative mini literature review with the beneficial properties of extra virgin olive oil and its polyphenols for possible prevention of Parkinson's disease.Method: To identify potentially relevant studies for the present mini-review, a search of the literature in databases (PubMed, Scopus and Web Of Science) was conducted during April 2021. The term "extra virgin Olive oil" was searched in combination with "Parkinson". The terms were searched in the title, abstract and keyword. No restrictions were applied as to the language or date of publication. Results and discussion:The sample consisted of 6 articles. When listing the articles found, beneficial effects of polyphenols in olive oil were evidenced, against brain oxidative damage caused by some toxins, in addition to triggering an autophagic response and interfering with the cell signaling pathways and mechanisms associated with cell function, survival or death. Conclusion:The beneficial effects of olive oil and its polyphenols in Parkinson's disease have been extensively researched and associated with the modulation of many cell pathways. Its ability to increase the antioxidant system and reduce inflammation has been linked to the protective effect in Parkinson's disease. Polyphenols have antioxidant power in vitro, studies in cell cultures; therefore, further in vivo studies are needed to confirm the protective effects of olive oil and its polyphenols on Parkinson's disease, in order to identify biologically relevant concentrations for therapeutic purposes.

Introdução. O resveratrol é um estilbeno encontrado em alguns alimentos. Os efeitos desse polifenol estão sendo cada vez mais estudados, devido ao seu potencial antioxidante e preventivo contra doenças neurodegenerativas. Além disso, sugere-se que a suplementação com resveratrol pode causar um efeito benéfico no humor. Objetivo. Esta revisão tem como objetivo avaliar ensaios clínicos randomizados que analisaram os efeitos do resveratrol no humor, por meio de suplementação oral. Método. Foram identificados estudos publicados até 20 de novembro de 2020 nas bases de dados PubMed, Web of Science e Scopus. Os critérios de inclusão foram: o termo resveratrol incluído no título, resumo ou palavra-chave; artigos em adultos saudáveis ​​ou mulheres saudáveis ​​no período pós-menopausa; tratamento apenas com suplementos orais. Esta revisão sistemática foi registrada no PROSPERO (CRD42020205072). A análise das evidências foi realizada pela ferramenta de avaliação do risco de viés (RoB 2.0). Resultados. Um total de 5 estudos envolvendo 339 participantes foram incluídos. Um estudo demonstrou resultados significantes, um na redução da fadiga, um na redução da ansiedade e dois no aumento do bem-estar geral. Nesses casos, o resveratrol demonstrou melhorar certos aspectos dos estados de humor; no entanto, a concordância entre os estudos é limitada. Conclusão. Com base nos resultados desta revisão, a literatura atual não fornece suporte suficiente para correlacionar a suplementação de resveratrol com melhora no humor, pesquisas com um tamanho amostral maior e alta qualidade metodológica são necessárias para medir a eficácia legítima do resveratrol no humor.

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